SECURITIES AND EXCHANGE COMMISSION

                                 WASHINGTON D.C. 20549

                                        FORM 11-K

          (Mark One)
          [ X ] ANNUAL REPORT PURSUANT TO SECTION 15(d) OF THE
                SECURITIES EXCHANGE ACT OF 1934 [FEE REQUIRED]

                For the fiscal year end December 31, 1993

                                          OR

          [   ] TRANSITION REPORT PURSUANT TO SECTION 15(d) OF THE
                SECURITIES EXCHANGE ACT OF 1934 [NO FEE REQUIRED]

          Commission file number 0-12477

                            AMGEN RETIREMENT AND SAVINGS PLAN
                                (Full title of the plan)

                                        AMGEN INC.
                            ---------------------------------
                         (Name of issuer of the securities held)

          1840 Dehavilland Drive, Thousand Oaks, California  91320-1789
          -------------------------------------------------------------
            (Address of principal executive offices)         (Zip Code)


          Exhibit filed with this report:

          Consent of Ernst & Young, Independent Auditors


                                       SIGNATURES

               Pursuant to the requirements of the Securities Exchange Act
          of 1934, the trustees have duly caused this annual report to be
          signed by the undersigned hereunto duly authorized.

                                          Amgen Retirement and Savings Plan
                                                     (Name of Plan)



          Date:      6/28/94            By:/s/LARRY A. MAY
               -----------------------     --------------------------------
                                            Larry A. May
                                            Vice President, Corporate
                                            Controller and Chief Accounting
                                            Officer of Amgen Inc.

                                                                 EXHIBIT




                  CONSENT OF ERNST & YOUNG, INDEPENDENT AUDITORS

          We consent to the incorporation by reference in the Registration
          Statement (Form S-8 No. 33-39104) pertaining to the Amgen 
          Retirement and Savings Plan and in the related Prospectus of
          our report dated June 23, 1994, with respect to the financial
          statements and supplemental schedules of the Amgen Retirement
          and Savings Plan included in this Annual Report (Form 11-K) for
          the year ended December 31, 1993.



          /s/ERNST & YOUNG
          Los Angeles, California
          June 28, 1994