Filed pursuant to Rule 424(b)(3) Registrant No. 333-88834 Prospectus Supplement No. 1 dated June 6, 2002 (To Prospectus dated May 31, 2002) $3,950,000,000 AMGEN INC. Liquid Yield Option(TM) Notes due 2032 (Zero Coupon--Senior) and Shares of Common Stock Issuable Upon Conversion of the Liquid Yield Option(TM) Notes ---------------- This document supplements the prospectus dated May 31, 2002, as amended and supplemented through the date hereof, relating to the resale by the holders of Liquid Yield Option(TM) Notes (Zero Coupon--Senior) (the "LYONs") due March 1, 2032 and the shares of our common stock into which the LYONs are convertible. This prospectus supplement is incorporated by reference into, and should be read in conjunction with, the prospectus dated May 31, 2002, including any amendments or supplements to it. This prospectus supplement is not complete without, and may not be delivered or utilized except in connection with, the prospectus, including any amendments or supplements to it. The table presented below sets forth information as of the date of this prospectus supplement about the principal amount at maturity of the LYONs and the underlying common stock beneficially owned by each selling security holder that may be offered using the prospectus. All of the information set forth in the table has been provided by the selling security holders on or prior to the date of this prospectus supplement and, to our knowledge, is true and correct as of the date of this prospectus supplement. However, the selling security holders may have sold, transferred or otherwise disposed of all or a portion of their LYONs since the date on which they provided the information regarding their LYONs. The table of selling security holders contained on pages 42-45 of the prospectus dated May 31, 2002 is hereby amended and replaced by the table set forth below. COMMON PRINCIPAL LYONS STOCK AMOUNT OF SHARES OF OWNED OWNED LYONS COMMON AFTER AFTER BENEFICIALLY STOCK COMMON COMPLETION COMPLETION OWNED AND BENEFICIALLY STOCK OF OF MATERIAL NAME OFFERED OWNED OFFERED(1) OFFERING(2) OFFERING(2) RELATIONSHIP(3) ---- ------------ ------------ ---------- ----------- ----------- --------------- Aid Association for Lutherans, as successor to Lutheran Brothershood....................... 11,000,000 97,461.1 97,461.1 -0- -- None Akela Capital Master Fund, LLC...... 2,000,000 17,720.2 17,720.2 -0- -- None Allstate Insurance Company.......... 21,900,000(4) 478,336.2(4) 194,036.2(4) -0-(4) 284,300(4) None Allstate Life Insurance Company..... 21,900,000(4) 478,336.2(4) 194,036.2(4) -0-(4) 284,300(4) None Alpha U.S. Sub Fund VIII, LLC....... 2,300,000 20,378.2 20,378.2 -0- -- None Amerisure Mutual Insurance Company............................ 975,000 8,638.6 8,638.6 -0- -- None Argent Classic Convertible Arbitrage Fund (Bermuda) Ltd................. 6,000,000 53,160.6 53,160.6 -0- -- None Argent Classic Convertible Arbitrage Fund L.P........................... 4,500,000 39,870.5 39,870.5 -0- -- None Argent LowLev Convertible Arbitrage Fund Ltd................. 13,500,000 119,611.4 119,611.4 -0- -- None 1

COMMON PRINCIPAL LYONS STOCK AMOUNT OF SHARES OF OWNED OWNED LYONS COMMON AFTER AFTER BENEFICIALLY STOCK COMMON COMPLETION COMPLETION OWNED AND BENEFICIALLY STOCK OF OF MATERIAL NAME OFFERED OWNED OFFERED(1) OFFERING(2) OFFERING(2) RELATIONSHIP(3) ---- ------------ ------------ ----------- ----------- ----------- --------------- Aristeia International Limited 26,950,000 238,779.7 238,779.7 -0- -- None Aristeia Trading LLC.......... 8,050,000 71,323.8 71,323.8 -0- -- None Associated Electric & Gas Insurance Services Limited... 3,000,000 26,580.3 26,580.3 -0- -- None Banc of America Securities LLC 9,281,000 82,230.6 82,230.6 -0- -- None Bank Austria Cayman Islands, Ltd.......................... 4,500,000 39,870.5 39,870.5 -0- -- None Bank of America Pension Plan.. 2,500,000 22,150.3 22,150.3 -0- -- None Bear, Stearns & Co. Inc....... 9,500,000 84,171.0 84,171.0 -0- -- None Black Diamond Capital I, Ltd.. 2,432,000 21,547.8 21,547.8 -0- -- None Black Diamond Convertible Offshore LDC................. 15,296,000 135,524.1 135,524.1 -0- -- None Black Diamond Offshore Ltd.... 8,647,000 76,613.3 76,613.3 -0- -- None Canyon Capital Arbitrage Masterfund, Ltd.............. 3,750,000 33,225.4 33,225.4 -0- -- None Canyon Mac 18, Ltd. (RMF)..... 625,000 5,537.6 5,537.6 -0- -- None Canyon Value Realization Fund (Cayman), Ltd................ 5,625,000 49,838.1 49,838.1 -0- -- None Canyon Value Realization Fund, L.P.................... 2,500,000 22,150.3 22,150.3 -0- -- None CDC Ixis Paris................ 15,000,000 132,901.5 132,901.5 -0- -- None Cobra Master Fund, Ltd........ 1,500,000 13,290.2 13,290.2 -0- -- None Continental Assistance Company on behalf of its Separate Account E........... 7,200,000 63,792.7 63,792.7 -0- -- None Continental Casualty Company.. 44,800,000 396,932.5 396,932.5 -0- -- None Credit Lyonnais SEC USA....... 28,000,000 248,082.8 248,082.8 -0- -- None DaimlerChrysler Corp Emp. #1 Pension Plan dtd 4/1/89...... 13,980,000 123,864.2 123,864.2 -0- -- None Deephaven Domestic Convertible Trading Ltd...... 165,850,000 1,469,447.6 1,469,447.6 -0- -- None DKR Fixed Income Holding Fund Ltd.......................... 3,000,000 26,580.3 26,580.3 -0- -- None Double Black Diamond Offshore LDC.......................... 50,469,000 447,160.4 447,160.4 -0- -- None First Union Securities Inc.... 20,000,000 177,202.0 177,202.0 -0- -- None Franklin and Marshall College. 785,000 6,955.2 6,955.2 -0- -- None Gain Offshore Master Fund Ltd. 6,450,000 57,147.6 57,147.6 -0- -- None Global Bermuda Limited Partnership.................. 7,000,000 62,020.7 62,020.7 -0- -- None Goldman Sachs and Company..... 14,670,000 129,977.7 129,977.7 -0- -- None Granville Capital Corporation. 45,000,000 398,704.5 398,704.5 -0- -- None HBK Master Fund, L.P.......... 17,000,000 172,821.7 150,621.7 -0- 22,200 None Highbridge International LLC.. 148,150,000 1,312,623.8 1,312,623.8 -0- -- None HSBC Trustee, Zola Managed Trust....................... 400,000 3,544.0 3,544.0 -0- -- None ING VP Convertible Fund....... 40,000 354.4 354.4 -0- -- None ING Convertible Fund.......... 3,960,000 35,086.0 35,086.0 -0- -- None Jersey (IMA) Ltd.............. 3,000,000 26,580.3 26,580.3 -0- -- None KBC Financial Products USA Inc.......................... 4,480,000 39,693.2 39,693.2 -0- -- None Lakeshore International, Ltd.. 28,000,000 248,082.8 248,082.8 -0- -- None Liberty View Fund LLC......... 2,000,000 17,720.2 17,720.2 -0- -- None Liberty View Funds L.P........ 9,000,000 79,740.9 79,740.9 -0- -- None Liberty View Global Volatility Fund.............. 26,000,000 230,362.6 230,362.6 -0- -- None Lyxor Master Fund............. 1,550,000 13,733.2 13,733.2 -0- -- None 2

COMMON PRINCIPAL LYONS STOCK AMOUNT OF SHARES OF OWNED OWNED LYONS COMMON AFTER AFTER BENEFICIALLY STOCK COMMON COMPLETION COMPLETION OWNED AND BENEFICIALLY STOCK OF OF MATERIAL NAME OFFERED OWNED OFFERED(1) OFFERING(2) OFFERING(2) RELATIONSHIP(3) ---- ------------- ------------ ------------ ----------- ----------- --------------- Lyxor Master Fund, c/o Zola Capital Management, LLC...... 4,750,000 42,085.5 42,085.5 -0- -- None Lyxor Master Fund Ref: Argent/ LowLev CB............ 3,000,000 26,580.3 26,580.3 -0- -- None Marathon Global Convertible Master Fund, Ltd............. 11,500,000 101,891.2 101,891.2 -0- -- None Merrill Lynch International Limited...................... 6,000,000 232,719.6 53,160.6 -0- 179,559 None Merrill Lynch, Pierce, Fenner & Smith, Inc................. 77,983,000 690,937.2 690,937.2 -0- -- None Morgan Stanley & Co........... 40,000,000 354,404.0 354,404.0 -0- -- None Nicholas Applegate Investment Grade Convertible............ 37,000 327.8 327.8 -0- -- None NMS Services (Cayman) Inc..... 50,000,000 443,005.0 443,005.0 -0- -- None Peoples Benefit Life Insurance Company Teamsters.. 7,500,000 66,450.8 66,450.8 -0- -- None Ramius Capital Group.......... 500,000 4,430.1 4,430.1 -0- -- None Ramius LP..................... 1,000,000 8,860.1 8,860.1 -0- -- None RCG Baldwin LP................ 1,500,000 13,290.2 13,290.2 -0- -- None RCG Halifax Master Fund, Ltd.. 1,500,000 13,290.2 13,290.2 -0- -- None RCG Latitude Master Fund, Ltd. 2,500,000 22,150.3 22,150.3 -0- -- None RCG Multi Strategy, LP........ 3,000,000 26,580.3 26,580.3 -0- -- None SAC Capital Associates, LLC... 27,500,000 343,652.8 243,652.8 -0- 100,000 None Salomon Smith Barney Inc...... 31,836,000 282,070.1 282,070.1 -0- -- None St. Albans Partners Ltd....... 5,000,000 44,300.5 44,300.5 -0- -- None State of Mississippi Health Care Trust Fund.............. 825,000 7,309.6 7,309.6 -0- -- None State Street Bank Custodian for GE Pension Trust......... 6,405,000 56,748.9 56,748.9 -0- -- None Susquehanna Capital Group..... 5,000,000 44,300.5 44,300.5 -0- -- None TD Securities (USA) Inc....... 65,000,000 575,906.5 575,906.5 -0- -- None Teachers Insurance & Annuity Association.................. 16,000,000 141,761.6 141,761.6 -0- -- None Tribecca Investments, LLC..... 60,000,000 531,606.0 531,606.0 -0- -- None UBS O'Connor LLC F/B/O O'Connor Global Convertible Portfolio.................... 750,000 6,645.1 6,645.1 -0- -- None UBS O'Connor LLC F/B/O UBS Global Equity Arbitrage Master Ltd................... 35,000,000 310,103.5 310,103.5 -0- -- None UBS Warburg LLC............... 24,060,000 213,174.0 213,174.0 -0- -- None UFJ Investments Asia Ltd...... 25,000,000 221,502.5 221,502.5 -0- -- None Wachovia Bank National Association.................. 20,000,000 177,202.0 177,202.0 -0- -- None Wachovia Securities International Ltd............ 31,000,000 274,663.1 274,663.1 -0- -- None White River Securities LLC.... 9,500,000 84,171.0 84,171.0 -0- -- None Worldwide Transactions Ltd.... 2,156,000 19,102.4 19,102.4 -0- -- None Yield Strategies Fund I, L.P.. 5,000,000 44,300.5 44,300.5 -0- -- None Yield Strategies Fund II, L.P. 5,000,000 44,300.5 44,300.5 -0- -- None Zola Partners, L.P............ 7,250,000 64,235.7 64,235.7 -0- -- None Other......................... 2,524,833,000 22,370,272.0 22,370,272.0 -0- -- None 3

- -------- (1)Represents shares of common stock issuable upon conversion of LYONs that are beneficially owned and offered by the selling security holder. (2)Assumes that all of the LYONs and/or all of the common stock into which the LYONs are convertible are sold. (3)Includes any position, office or other material relationship which the selling security holder has had within the past three years with Amgen or any of its predecessors or affiliates. (4)Allstate Insurance Company and Allstate Life Insurance Company are affiliated entities. Allstate Insurance Company is the record owner of $4,000,000 principal amount of LYONs and Allstate Life Insurance Company is the record owner of $17,900,000 principal amount of LYONs. Aside from the LYONs and the common stock into which the LYONs are convertible, Allstate Insurance Company is the record owner of 180,300 shares of our common stock and Allstate Insurance Company and its affiliates beneficially own an aggregate of 284,300 shares of our common stock. ---------------- See "Risk Factors" section beginning on page 8 of the prospectus to read about factors you should consider before purchasing the LYONs or our common stock. ---------------- NEITHER THE SECURITIES AND EXCHANGE COMMISSION NOR ANY STATE SECURITIES COMMISSION HAS APPROVED OR DISAPPROVED OF THESE SECURITIES OR PASSED UPON THE ADEQUACY OR ACCURACY OF THIS PROSPECTUS. ANY REPRESENTATION TO THE CONTRARY IS A CRIMINAL OFFENSE. The date of this prospectus supplement is June 6, 2002. - -------- (TM) Trademark of Merrill Lynch & Co., Inc. 4