SEC Form 4

FORM 4		UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940	OMB APPROVAL OMB Number: 3235-0287 Estimated average burden hours per response: 0.5
	Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

1. Name and Address of Reporting Person* SHARER KEVIN W (Last) (First) (Middle) ONE AMGEN CENTER DRIVE (Street) THOUSAND OAKS CA 91320-1799 (City) (State) (Zip)	2. Issuer Name and Ticker or Trading Symbol AMGEN INC [ AMGN ]	5. Relationship of Reporting Person(s) to Issuer (Check all applicable) X Director 10% Owner X Officer (give title below) Other (specify below) Chairman of the Bd, CEO & Pres
	3. Date of Earliest Transaction (Month/Day/Year) 11/08/2005
	4. If Amendment, Date of Original Filed (Month/Day/Year)	6. Individual or Joint/Group Filing (Check Applicable Line) X Form filed by One Reporting Person Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Common Stock	11/08/2005		S		4,100	D	$79.7137	344,799	D
Common Stock	11/08/2005		S		5,535	D	$79.7928	339,264	D
Common Stock	11/08/2005		S		4,550	D	$79.8131	334,714	D
Common Stock	11/08/2005		S		5,100	D	$79.8333	329,614	D
Common Stock	11/08/2005		S		3,948	D	$79.9439	325,666	D
Common Stock	11/08/2005		S		3,500	D	$80.0426	322,166	D
Common Stock	11/08/2005		S		3,004	D	$80.0527	319,162	D
Common Stock	11/08/2005		S		5,330	D	$80.0626	313,832	D
Common Stock	11/08/2005		S		1,996	D	$80.063	311,836	D
Common Stock	11/08/2005		S		31	D	$80.09	311,805	D
Common Stock	11/08/2005		S		70	D	$80.12	311,735	D
Common Stock	11/08/2005		S		2,750	D	$80.1233	308,985	D
Common Stock	11/08/2005		S		90	D	$80.13	308,895	D
Common Stock	11/08/2005		S		2,600	D	$80.1323	306,295	D
Common Stock	11/08/2005		S		3,609	D	$80.1339	302,686	D
Common Stock	11/08/2005		S		3,716	D	$80.1535	298,970	D
Common Stock	11/08/2005		S		4,600	D	$80.1733	294,370	D
Common Stock	11/08/2005		S		3,400	D	$80.1932	290,970	D
Common Stock	11/08/2005		S		3,700	D	$80.2224	287,270	D
Common Stock	11/08/2005		S		500	D	$80.382	286,770	D
Common Stock	11/08/2005		S		19	D	$80.39	286,751	D
Common Stock	11/08/2005		S		4,208	D	$80.472	282,543	D
Common Stock	11/08/2005		S		4,002	D	$80.5223	278,541	D
Common Stock	11/08/2005		S		4,389	D	$80.5224	274,152	D
Common Stock	11/08/2005		S		6,300	D	$80.6822	267,852	D
Common Stock	11/08/2005		S		6,102	D	$80.7128	261,750	D
Common Stock								3,224.201(1)	I	By 401(k) Plan
Common Stock								122,595	I	Living Trust

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares

Explanation of Responses:

1. These are units acquired under the Company's 401(k) Plan and represent interests in the Company's stock fund as of September 30, 2005.

	/s/ KEVIN W SHARER	11/10/2005
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
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