United States securities and exchange commission logo May 10, 2024 Peter Griffith Executive Vice President and Chief Financial Officer Amgen Inc. One Amgen Center Drive Thousand Oaks, CA 91320 Re: Amgen Inc. Form 10-K for Fiscal Year Ended December 31, 2023 File No. 001-37702 Dear Peter Griffith: We have completed our review of your filings. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Sincerely, Division of Corporation Finance Office of Life Sciences