0000318154-26-000113 | 11-K | XBRL Viewer

EBP, Reconciliation of Financial Statement to Form 5500 [Line Items]

EBP, Reconciliation of Financial Statement to Form 5500

The reconciliation of net assets available for benefits per the financial statements to the Form 5500 consisted of the following:


	December 31,
	2025		2024
Net assets available for benefits per the financial statements	$	8,963,481,280	$	7,755,448,034
Adjustment to fair value for fully benefit-responsive investment contracts	(14,721,978)		(37,044,409)
Amounts allocated to withdrawing participants	(1,342,012)		(2,576,951)
Deemed loans	(458,166)		(405,772)
Net assets per the Form 5500	$	8,946,959,124	$	7,715,420,902

The following is a reconciliation of the net investment gain per the financial statements to the Form 5500:


	Year Ended
	December 31, 2025
Interest and dividend income	$	58,852,063
Net realized/unrealized gains	1,207,787,460
Net investment gain per the financial statements	1,266,639,523
Adjustment from fair value to contract value for fully benefit-responsive investment contracts:
Prior-year adjustment	37,044,409
Current-year adjustment	(14,721,978)
Total net investment gain per the Form 5500	$	1,288,961,954

The following is a reconciliation of expenses per the financial statements to the Form 5500:


	Year Ended
	December 31, 2025
Benefits paid	$	(640,689,220)
Investment and administrative fees	(8,193,031)
Total expenses per the financial statements	(648,882,251)
Amounts allocated to withdrawing participants at December 31, 2024	2,576,951
Amounts allocated to withdrawing participants at December 31, 2025	(1,342,012)
Deemed loans at December 31, 2024	405,772
Deemed loans at December 31, 2025	(458,166)
Total expenses per the Form 5500	$	(647,699,706)

Employee Benefit Plan, Schedule, Asset Held for Investment

12 Months Ended

Dec. 31, 2025

EBP, Schedule of Asset Held for Investment [Line Items]

Schedule H, line 4i – Schedule of Assets (Held at End of Year)

Supplemental Schedule

Amgen Retirement and Savings Plan

EIN: 95-3540776 Plan: #001

As of December 31, 2025

Schedule H, line 4i – Schedule of Assets (Held at End of Year)

Identity of Issue

Description of Investment

Current Value

Amgen stock*

Employer Securities

417,689,989

Capital Preservation Asset Class:

Galliard Intermediate Core Fund L*

Collective Trust Fund

461,962,001

Galliard Short Core Fund F*

Collective Trust Fund

284,401,501

Short-Term Investment Fund II*

Collective Trust Fund

39,787,146

NT Collective Short Term Investment Fund*

Collective Trust Fund

53,050,433

Wrapper Contracts

—

Total Capital Preservation Asset Class

839,201,081

Fixed Income Active Asset Class:

Wellington Core Bond Plus Portfolio Collective Investment Trust II*

Collective Trust Fund

182,810,908

FIAM Group Trust For Employees Benefit Plan Core Plus Commingled Pool Class W*

Collective Trust Fund

181,975,209

BBH Collective Investment Series Trust Series Fund Income Class 1*

Collective Trust Fund

181,868,204

NT Collective Aggregate Bond Index Fund / Non Lending*

Collective Trust Fund

65,981,875

Banc America Alternative Loan Trust Series 2004-6 Class 4A 15.0% Due 10-25-2048*

Corporate Bond

1,941

GMAC Mortgage Loan Trust 2003/J10 4.75% Due 01/25/2019

Corporate Bond

743

NT Collective Short Term Investment Fund*

Collective Trust Fund

282

Master Asset Security Trust 2004/6 5.25% Due 07/25/2019

Corporate Bond

Total Fixed Income Active Asset Class

612,639,163

Fixed Income Index Asset Class:

NT Collective Aggregate Bond Index Fund / Non Lending*

Collective Trust Fund

970,311,143

Total Fixed Income Index Asset Class

970,311,143

U.S. Equity Active Asset Class:

Nuveen Winslow Large Capital Growth Fund Class C*

Collective Trust Fund

220,498,952

Blackrock Instituitional Trust Company Investment Funds Russell 3000 Alpha Tilts Fund F*

Collective Trust Fund

166,892,573

Boston Partners CIT Large Capital Value Class E*

Collective Trust Fund

157,416,376

NT Collective Russell 3000 Index Fund / Non Lending*

Collective Trust Fund

20,089,652

Clean Harbors Inc.

Common and Preferred Stock

3,650,854

Coherent Corporation

Common and Preferred Stock

3,403,840

Ametek Inc.

Common and Preferred Stock

3,249,236

SS&C Technologies Holdings Inc.

Common and Preferred Stock

3,243,020

Waste Connections Inc.

Common and Preferred Stock

3,130,702

Entegris Inc.

Common and Preferred Stock

2,955,069

BWX Technologies Inc.

Common and Preferred Stock

2,795,341

NT Collective Short Term Investment Fund*

Collective Trust Fund

2,398,246

Huntington Bancshares Inc.

Common and Preferred Stock

2,336,420

Identity of Issue

Description of Investment

Current Value

Woodward Inc.

Common and Preferred Stock

2,274,353

UGI Corporation

Common and Preferred Stock

2,240,897

Rentokil Initial PLC

Common and Preferred Stock

2,075,015

Charles River Laboratories International Inc.

Common and Preferred Stock

1,950,515

Bio-Techne Corporation

Common and Preferred Stock

1,926,851

Keysight Technologies Inc.

Common and Preferred Stock

1,893,528

Amphenol Corporation Class A

Common and Preferred Stock

1,882,230

Ingredion Inc.

Common and Preferred Stock

1,866,481

Halozyme Therapeutics Inc.

Common and Preferred Stock

1,864,075

Henry Schein Inc.

Common and Preferred Stock

1,819,211

Brown & Brown Inc.

Common and Preferred Stock

1,796,916

Heico Corporation Class A

Common and Preferred Stock

1,705,417

Dolby Laboratories Inc.

Common and Preferred Stock

1,624,381

Shift4 Payments Inc. Class A

Common and Preferred Stock

1,574,375

IDEX Corporation

Common and Preferred Stock

1,524,768

STERIS plc

Common and Preferred Stock

1,507,176

LKQ Corporation

Common and Preferred Stock

1,359,453

Power Integrations Inc.

Common and Preferred Stock

1,340,071

Prosperity Bancshares Inc.

Common and Preferred Stock

1,220,759

WEX Inc.

Common and Preferred Stock

1,205,844

Hexcel Corporation

Common and Preferred Stock

1,172,941

HealthEquity Inc.

Common and Preferred Stock

1,156,118

Casella Waste Systems Inc. Class A

Common and Preferred Stock

1,092,717

Mid-American Apartment Communities Inc.

Common and Preferred Stock

1,084,609

Allegion PLC

Common and Preferred Stock

1,072,506

Cabot Corporation

Common and Preferred Stock

1,040,662

Graco Inc.

Common and Preferred Stock

998,886

RBC Bearings Inc.

Common and Preferred Stock

900,447

Procore Technologies Inc.

Common and Preferred Stock

880,154

First American Financial Corporation

Common and Preferred Stock

854,385

Copart Inc.

Common and Preferred Stock

833,308

Ensign Group Inc.

Common and Preferred Stock

809,856

Federal Signal Corporation

Common and Preferred Stock

727,119

National Retail Properties Inc.

Common and Preferred Stock

724,159

Fabrinet Company

Common and Preferred Stock

720,253

Nova Measuring Instruments

Common and Preferred Stock

716,875

Medpace Holdings Inc.

Common and Preferred Stock

713,857

Bank Ozk

Common and Preferred Stock

667,566

EnPro Inc.

Common and Preferred Stock

647,743

Moelis & Company Class A

Common and Preferred Stock

615,567

SiteOne Landscape Supply Inc.

Common and Preferred Stock

613,333

Paymentus Holdings Inc. Class A

Common and Preferred Stock

593,829

Standex International Corporation

Common and Preferred Stock

567,101

Kadant Inc.

Common and Preferred Stock

565,195

Ollies Bargain Outlet Holdings Inc.

Common and Preferred Stock

527,005

Balchem Corporation

Common and Preferred Stock

525,105

Loar Holdings Inc.

Common and Preferred Stock

521,968

Camtek Limited

Common and Preferred Stock

519,283

CSW Industrials Inc.

Common and Preferred Stock

510,742

Everus Construction Group Inc.

Common and Preferred Stock

491,799

Saia Inc.

Common and Preferred Stock

490,107

Modine Manufacturing Company

Common and Preferred Stock

486,243

Identity of Issue

Description of Investment

Current Value

CCC Intelligent Solutions Holdings Inc.

Common and Preferred Stock

478,272

ICF International, Inc.

Common and Preferred Stock

473,074

Global-E Online Limited

Common and Preferred Stock

468,772

Hamilton Lane Inc. Class A

Common and Preferred Stock

453,565

Markel Corporation Holding Company

Common and Preferred Stock

451,427

Five Below Inc.

Common and Preferred Stock

447,167

Clearwater Analytics Holdings Inc. Class A

Common and Preferred Stock

421,015

Guidewire Software Inc.

Common and Preferred Stock

415,890

XPEL Inc.

Common and Preferred Stock

396,435

Certara Inc.

Common and Preferred Stock

344,524

Wingstop Inc.

Common and Preferred Stock

336,986

RLI Corporation

Common and Preferred Stock

332,312

Arhaus Inc. Class A

Common and Preferred Stock

327,444

Valvoline Inc.

Common and Preferred Stock

325,356

Q2 Holdings Inc.

Common and Preferred Stock

317,576

UFP Industries Inc.

Common and Preferred Stock

306,839

Novanta Inc.

Common and Preferred Stock

296,642

Freshpet Inc.

Common and Preferred Stock

289,600

Morningstar Inc.

Common and Preferred Stock

282,720

Floor & Decor Holdings Inc.

Common and Preferred Stock

268,464

Goosehead Insurance Inc. Class A

Common and Preferred Stock

256,965

Trex Company Inc.

Common and Preferred Stock

245,735

AAON Inc.

Common and Preferred Stock

236,223

Cohen & Steers Inc.

Common and Preferred Stock

222,492

Bellring Brands Inc.

Common and Preferred Stock

190,130

Vita Coco Company Inc.

Common and Preferred Stock

100,878

Pool Corporation

Common and Preferred Stock

64,736

Total U.S. Equity Active Asset Class

659,305,274

U.S. Equity Index Asset Class:

NT Collective Russell 3000 Index Fund / Non Lending*

Collective Trust Fund

2,598,695,401

Total U.S. Equity Index Asset Class

2,598,695,401

International Equity Active Asset Class:

Dodge & Cox International Stock Fund

Mutual Fund

255,411,543

Mawer International Equity Collective Investment Trust Class B*

Collective Trust Fund

252,538,156

Great Grey Trust Company
GQG Partners International Equity
CIT Class C*

Collective Trust Fund

248,729,768

Mondrian Master CIT Focused All Countries World ex-US Equity*

Collective Trust Fund

248,622,909

Wilmington Trust Collective Investment Trust / Jennison International Equity Opportunities CIT Class J*

Collective Trust Fund

248,011,296

NT Collective MSCI All Country World Index (ACWI) ex/US Index Fund / Non Lending*

Collective Trust Fund

50,754,829

Total International Equity Active Asset Class

1,304,068,501

International Equity Index Asset Class:

NT Collective MSCI All Country World Index (ACWI) ex/US Index Fund / Non Lending*

Collective Trust Fund

384,229,509

Total International Equity Index Asset Class

384,229,509

Identity of Issue

Description of Investment

Current Value

Participant Self-Directed Accounts

Various Investments

1,119,760,757

Notes Receivable from Participants*

Interest Rate 4.25% - 9.50%

38,602,548

Other:

Tax Reclaims

Cash and Cash Equivalents

2,662,444

ML Vanguard Federal Money Market Forfeiture / Settlement*

Cash and Cash Equivalents

1,378,351

BIF Money Fund*

Cash and Cash Equivalents

1,342,037

NT Collective Short Term Investment Fund*

Collective Trust Fund

475,614

Interest Bearing Cash

Cash and Cash Equivalents

88,742

Exide Technologies

Common and Preferred Stock

24,978

Total Other

5,972,166

Grand Total

8,950,475,532

* Indicates party-in-interest

Fair Value Measurements (Details) - EBP 001 - USD ($)	Dec. 31, 2025	Dec. 31, 2024
EBP, Investment, Fair Value and NAV [Line Items]
Total investments at fair value	$ 8,165,509,482	$ 7,032,543,261
Total
EBP, Investment, Fair Value and NAV [Line Items]
Total investments at fair value	8,165,509,482	7,032,543,261
Total \| Amgen stock
EBP, Investment, Fair Value and NAV [Line Items]
Total investments at fair value	417,689,989	344,055,715
Total \| Cash and cash equivalents
EBP, Investment, Fair Value and NAV [Line Items]
Total investments at fair value	5,471,574	3,466,558
Total \| Collective trust funds
EBP, Investment, Fair Value and NAV [Line Items]
Total investments at fair value	6,275,138,481	5,003,198,779
Total \| Common and preferred stocks
EBP, Investment, Fair Value and NAV [Line Items]
Total investments at fair value	92,034,453	533,256,711
Total \| Debt securities
EBP, Investment, Fair Value and NAV [Line Items]
Total investments at fair value	2,685	2,979
Total \| Mutual funds
EBP, Investment, Fair Value and NAV [Line Items]
Total investments at fair value	255,411,543	148,845,846
Total \| Self-directed brokerage accounts
EBP, Investment, Fair Value and NAV [Line Items]
Total investments at fair value	1,119,760,757	999,716,673
Quoted prices in active markets for identical assets (Level 1)
EBP, Investment, Fair Value and NAV [Line Items]
Total investments at fair value	1,887,625,908	2,026,022,128
Quoted prices in active markets for identical assets (Level 1) \| Amgen stock
EBP, Investment, Fair Value and NAV [Line Items]
Total investments at fair value	417,689,989	344,055,715
Quoted prices in active markets for identical assets (Level 1) \| Cash and cash equivalents
EBP, Investment, Fair Value and NAV [Line Items]
Total investments at fair value	5,471,574	3,466,558
Quoted prices in active markets for identical assets (Level 1) \| Collective trust funds
EBP, Investment, Fair Value and NAV [Line Items]
Total investments at fair value	0	0
Quoted prices in active markets for identical assets (Level 1) \| Common and preferred stocks
EBP, Investment, Fair Value and NAV [Line Items]
Total investments at fair value	92,034,453	533,256,711
Quoted prices in active markets for identical assets (Level 1) \| Debt securities
EBP, Investment, Fair Value and NAV [Line Items]
Total investments at fair value	0	0
Quoted prices in active markets for identical assets (Level 1) \| Mutual funds
EBP, Investment, Fair Value and NAV [Line Items]
Total investments at fair value	255,411,543	148,845,846
Quoted prices in active markets for identical assets (Level 1) \| Self-directed brokerage accounts
EBP, Investment, Fair Value and NAV [Line Items]
Total investments at fair value	1,117,018,349	996,397,298
Significant other observable inputs (Level 2)
EBP, Investment, Fair Value and NAV [Line Items]
Total investments at fair value	6,277,883,574	5,006,521,133
Significant other observable inputs (Level 2) \| Amgen stock
EBP, Investment, Fair Value and NAV [Line Items]
Total investments at fair value	0	0
Significant other observable inputs (Level 2) \| Cash and cash equivalents
EBP, Investment, Fair Value and NAV [Line Items]
Total investments at fair value	0	0
Significant other observable inputs (Level 2) \| Collective trust funds
EBP, Investment, Fair Value and NAV [Line Items]
Total investments at fair value	6,275,138,481	5,003,198,779
Significant other observable inputs (Level 2) \| Common and preferred stocks
EBP, Investment, Fair Value and NAV [Line Items]
Total investments at fair value	0	0
Significant other observable inputs (Level 2) \| Debt securities
EBP, Investment, Fair Value and NAV [Line Items]
Total investments at fair value	2,685	2,979
Significant other observable inputs (Level 2) \| Mutual funds
EBP, Investment, Fair Value and NAV [Line Items]
Total investments at fair value	0	0
Significant other observable inputs (Level 2) \| Self-directed brokerage accounts
EBP, Investment, Fair Value and NAV [Line Items]
Total investments at fair value	2,742,408	3,319,375
Significant unobservable inputs (Level 3)
EBP, Investment, Fair Value and NAV [Line Items]
Total investments at fair value	0	0
Significant unobservable inputs (Level 3) \| Amgen stock
EBP, Investment, Fair Value and NAV [Line Items]
Total investments at fair value	0	0
Significant unobservable inputs (Level 3) \| Cash and cash equivalents
EBP, Investment, Fair Value and NAV [Line Items]
Total investments at fair value	0	0
Significant unobservable inputs (Level 3) \| Collective trust funds
EBP, Investment, Fair Value and NAV [Line Items]
Total investments at fair value	0	0
Significant unobservable inputs (Level 3) \| Common and preferred stocks
EBP, Investment, Fair Value and NAV [Line Items]
Total investments at fair value	0	0
Significant unobservable inputs (Level 3) \| Debt securities
EBP, Investment, Fair Value and NAV [Line Items]
Total investments at fair value	0	0
Significant unobservable inputs (Level 3) \| Mutual funds
EBP, Investment, Fair Value and NAV [Line Items]
Total investments at fair value	0	0
Significant unobservable inputs (Level 3) \| Self-directed brokerage accounts
EBP, Investment, Fair Value and NAV [Line Items]
Total investments at fair value	$ 0	$ 0

Summary of Significant Accounting Policies (Details) - EBP 001 - USD ($)	Dec. 31, 2025	Dec. 31, 2024
EBP, Accounting Standard Update and Change in Accounting Principle [Line Items]
Total fully benefit-responsive investment contracts	$ 761,085,480	$ 688,059,315
Synthetic investment contracts
EBP, Accounting Standard Update and Change in Accounting Principle [Line Items]
Total fully benefit-responsive investment contracts	$ 761,085,480	$ 688,059,315

Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

Cover	12 Months Ended
Cover	Dec. 31, 2025
Document Information [Line Items]
Document Type	11-K
Entity Registrant Name	AMGEN INC.
Amendment Flag	false
Entity Central Index Key	0000318154
EBP 001
Document Information [Line Items]
Document Type	11-K
Entity Registrant Name	AMGEN INC.
Amendment Flag	false
Entity Central Index Key	0000318154

Reconciliation of Financial Statements to Form 5500 (Details) - EBP 001 - USD ($)	Dec. 31, 2025	Dec. 31, 2024
EBP, Reconciliation of Financial Statement to Form 5500 [Line Items]
Net assets available for benefits per the financial statements	$ 8,963,481,280	$ 7,755,448,034
Adjustment to fair value for fully benefit-responsive investment contracts	(14,721,978)	(37,044,409)
Amounts allocated to withdrawing participants	(1,342,012)	(2,576,951)
Deemed loans	(458,166)	(405,772)
Net assets per the Form 5500	$ 8,946,959,124	$ 7,715,420,902

Amount of asset less liability available to pay benefit of participant in employee stock purchase, saving, or similar plan (employee benefit plan (EBP)), including, but not limited to, aggregation of participants' individual account balances.

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Reference 2: http://www.xbrl.org/2003/role/disclosureRef
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Reference 10: http://www.xbrl.org/2003/role/disclosureRef
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Reconciliation of Financial Statements to Form 5500 - Reconciliation of Net Income (Details) - EBP 001	12 Months Ended
	Dec. 31, 2025 USD ($)
EBP, Reconciliation of Financial Statement to Form 5500 [Line Items]
Interest and dividend income	$ 58,852,063
Net realized/unrealized gains	1,207,787,460
Net increase in net assets available for benefits per the financial statements	1,266,639,523
Prior-year adjustment	37,044,409
Current-year adjustment	(14,721,978)
Net income per the Form 5500	$ 1,288,961,954

Summary of Significant Accounting Policies (Tables)

12 Months Ended

Dec. 31, 2025

EBP, Accounting Standard Update and Change in Accounting Principle [Line Items]

Fully Benefit-Responsive Investment Contract

The contract values of the Plan’s synthetic investment contracts were as follows:


	December 31,
	2025		2024
Synthetic investment contracts	$	761,085,480	$	688,059,315

Total fully benefit-responsive investment contracts	$	761,085,480	$	688,059,315

Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

Statements of Net Assets Available for Benefits - EBP 001 - USD ($)	Dec. 31, 2025	Dec. 31, 2024
Assets
Investments at fair value	$ 8,165,509,482	$ 7,032,543,261
Investments in fully benefit-responsive investment contracts at contract value	761,085,480	688,059,315
Notes receivable from participants	39,060,714	35,591,211
Other – principally due from broker	5,929,112	3,433,090
Total assets	8,971,584,788	7,759,626,877
Liabilities
Other – principally due to broker	8,103,508	4,178,843
Total liabilities	8,103,508	4,178,843
Net assets available for benefits	$ 8,963,481,280	$ 7,755,448,034

Description of Plan	12 Months Ended
Description of Plan	Dec. 31, 2025
EBP 001
EBP, Description of Plan [Line Items]
Description of Plan	Description of the Plan The following description of the Amgen Retirement and Savings Plan (the Plan) provides only general information. Participants should refer to the Plan document for a more complete description of the Plan’s provisions. General The Plan was established effective April 1, 1985, was amended and restated effective January 1, 2017, and was subsequently amended with the most recent amendment effective on or prior to December 31, 2025 adopted on March 5, 2025. The Plan was subsequently amended and restated effective January 1, 2026. The Plan is a defined contribution plan covering substantially all domestic employees of Amgen Inc. (the Company or Amgen) and participating subsidiaries. The Plan is intended to qualify under sections 401(a) and 401(k) of the Internal Revenue Code of 1986 (the Code) (see Note 4, Income Tax Status) and section 407(d)(3)(A) of the Employee Retirement Income Security Act of 1974 (ERISA). Contributions Subject to certain limitations (as defined in the Plan), participants may elect to contribute up to 30% of their eligible compensation in pre-tax contributions, Roth contributions (in accordance with the Code), after-tax contributions or a combination of these types of contributions (together, Individual Contributions). A participant’s combined pre-tax contributions and Roth contributions (exclusive of catch-up contributions discussed below) are subject to Internal Revenue Service (IRS) and Plan limits and could not exceed a maximum of $23,500 in 2025. Participant after-tax contributions are subject to IRS and Plan limitations and could not exceed a maximum of $11,500 in 2025. Unless an employee has voluntarily enrolled in the Plan or has declined to participate in the Plan within the first 30 days of employment, all newly eligible participants are automatically enrolled in the Plan, and contributions equal to 5% of their eligible compensation are withheld and contributed to the Plan as pre-tax contributions; such contributions are automatically increased by 1% per year until their contributions reach 10% of their eligible compensation. Participants may elect to adjust, cease or resume their Individual Contributions at any time. Participants who are at least age 50 by the close of the Plan year may also elect to make certain additional Individual Contributions, referred to as catch-up contributions, that are subject to IRS and Plan limitations and could not exceed $7,500 in 2025, or $11,250 in 2025 for participants who attain ages 60 through 63 during the Plan year. Catch-up contributions may be made as pre-tax contributions, Roth contributions or a combination of these types of contributions. Participants may also contribute pre-tax, Roth and after-tax amounts representing distributions from certain retirement plans qualified in the United States or certain individual retirement accounts (IRAs), referred to as rollover contributions (as defined in the Plan). Each pay period, the Company makes a non-elective contribution for all eligible participants, whether or not they have elected to make Individual Contributions to the Plan, equal to 5% of each participant’s eligible compensation (Core Contributions) up to a maximum of $17,500 in 2025. In addition, the Company makes a contribution equal to amounts contributed by the participant as pre-tax contributions or Roth contributions, including such contributions designated as catch-up contributions, of up to 5% of eligible compensation (Matching Contributions) up to a maximum of $17,500 in 2025. Also, the Company can, at its discretion, make a special contribution (Special Contribution) on behalf of a participant who is in his or her initial year of employment with the Company and who could not make the maximum participant contribution permitted under the Plan because in the same Plan year he or she previously made pre-tax salary deferrals under a prior unrelated employer’s qualified plan. Participants select the investments in which their Individual Contributions, including their Core Contributions, Matching Contributions and Special Contributions, if any, (collectively, Company Contributions) are to be invested, electing among various alternatives, including Amgen common stock (Amgen stock). Participants may direct a maximum of 20% of contributions to be invested in Amgen stock. In addition, participants may transfer amounts among the investment options at any time, subject to certain limitations. Notwithstanding the foregoing, if 20% or more of the value of a participant’s Plan account is invested in Amgen stock, the Plan document provides that no transfers from other investment options can be made to invest in Amgen stock. The accounts of participants who have not made an investment election are allocated to investments under a qualified default investment alternative, which is intended to be compliant with ERISA regulations. At any time, participants may elect to alter the investments in their accounts made under a qualified default investment alternative. Vesting and Forfeitures Participants are immediately vested with respect to their Individual Contributions, Matching Contributions and Special Contributions, if any, and earnings and losses (hereafter referred to as earnings) thereon. Participants hired prior to January 1, 2020, are also immediately vested with respect to their Core Contributions and earnings thereon. Participants hired on or after January 1, 2020, vest in full with respect to their Core Contributions and earnings thereon after three years of service, as defined by the terms of the Plan, or upon reaching age 65 while employed by Amgen, if earlier. If a participant ceases to be an employee before fully vesting in their account, the non-vested Core Contributions and earnings thereon of the participant’s account is treated as a forfeiture, as defined by the terms of the Plan, on the earlier of (a) the date the participant incurs a five-year break in service, as defined by the terms of the Plan or, (b) the date the participant receives a distribution of the entire vested portion of their account. Forfeitures are applied, in accordance with Plan provisions, to reduce Core or Matching Contributions, to reinstate forfeitures of reemployed participants, to reinstate the accounts of lost participants or beneficiaries (as defined in the Plan), to reduce Plan administrative expenses for the current or immediately following Plan year, and/or for any other purpose permitted under federal regulations or other applicable authority. Participant Accounts Each participant’s account is credited with: (a) the participant’s Individual Contributions; (b) an allocation of Company Contributions; and (c) earnings. The benefit to which a participant is entitled is the benefit that can be provided from the participant’s account. Plan Investments Plan participants can invest in seven different asset classes as well as Amgen stock or can actively manage their account under a self-directed brokerage arrangement in which a wider array of investment options are available. The value of an investment in an asset class is determined by its underlying investment vehicles, which may include one or more of the following: mutual funds, collective trust funds and portfolios which are separately managed exclusively for the benefit of Plan participants and their beneficiaries (separately managed portfolios). The separately managed portfolios invest in various types of assets, including publicly traded common and preferred stocks, collective trust funds and investment contracts. The asset classes are designed to provide participants with choices among a variety of investment objectives. Payments of Benefits Subject to Plan limitations, upon termination of employment, including termination due to disability (as defined in the Plan) or retirement, participants may elect to receive a full or partial distribution of their account balance in: (a) a single payment in cash; (b) a single distribution in full shares of Amgen stock (with any fractional shares paid in cash); (c) a single distribution paid in a combination of cash and full shares of Amgen stock; (d) cash installments over 10 years; or (e) a rollover distribution to an eligible retirement plan. Participants may also elect to maintain their account balance in the Plan subsequent to termination of employment, provided that their account balance is greater than $1,000. If a participant dies before receiving the value of his or her account balance, the participant’s beneficiary may elect to receive the distribution of remaining funds from among the alternatives described above, subject to certain Plan limitations. No withdrawals may be made from the Plan while a participant continues to be employed by the Company except in certain circumstances including, but not limited to, financial hardship, disability and attainment of age 59 1/2. Amgen Stock Dividends Participants that invest in Amgen stock may elect to receive distributions of cash with respect to dividends the Company pays on Amgen stock or reinvest such dividends to acquire additional shares of Amgen stock. Notes Receivable from Participants Subject to certain restrictions, a participant can have up to two loans outstanding at any one time from his or her Plan account with a combined maximum loan amount that may not exceed the lesser of: (a) 50% of the participant’s account balance (exclusive of amounts related to Roth contributions and earnings thereon) or (b) $50,000 less certain adjustments, as applicable (as defined in the Plan). A participant’s loan is secured by his or her Plan account balance. Loans bear interest at fixed rates which, until changed by the Company, are based on the prime rate plus one percentage point as published in The Wall Street Journal, determined as of the last day of the calendar quarter preceding origination or such other rate as may be required by law. Loans are generally payable in installments over periods of up to five years, unless the loan is used to acquire a principal residence for which the term of the loan may be up to 20 years. Principal and interest payments are allocated to the participant’s account. Plan Termination Although it has not expressed any intent to do so, the Company has the right under the Plan to terminate the Plan subject to the provisions of ERISA. Upon termination, participants would become fully vested in Core Contributions and receive distributions of their account balances. Trustees and Custodians Bank of America, N.A. is the Plan’s trustee and custodian with respect to the self-directed brokerage arrangement and the Amgen common stock fund. The Northern Trust Company, NA (Northern) is the Plan’s trustee and custodian with respect to the asset classes.

Description of Plan (Details) - EBP 001	12 Months Ended
Description of Plan (Details) - EBP 001	Dec. 31, 2025 USD ($) year class Loan
EBP, Description of Plan [Line Items]
Maximum annual compensation to total compensation, percentage	30.00%
Automatic deferral rate, annual increase	1.00%
Participant compensation matched, percentage	5.00%
Maximum contribution to Amgen stock, percentage	20.00%
Vesting period	3 years
Maximum vesting age \| year	65
Break in service period	5 years
Number of asset classes \| class	7
Cash installment period	10 years
Involuntary cash-out limit	$ 1,000
Maximum number of loans outstanding \| Loan	2
Maximum borrowing, to total account, percentage	50.00%
Maximum borrowing amount	$ 50,000
Basis spread on variable rate	1.00%
General loan, borrowing term	5 years
Primary residence, borrowing term	20 years
Minimum
EBP, Description of Plan [Line Items]
Automatic deferral rate	5.00%
Maximum
EBP, Description of Plan [Line Items]
Automatic deferral rate	10.00%

Fair Value Measurements (Tables)

12 Months Ended

Dec. 31, 2025

EBP, Investment, Fair Value and NAV [Line Items]

EBP, Investment, Fair Value and NAV

The following fair value hierarchy tables present information about each major class/category of the Plan’s investments measured at fair value:


	Fair value measurements at December 31, 2025, using
	Quoted prices in active markets for identical assets (Level 1)		Significant other observable inputs (Level 2)		Significant unobservable inputs (Level 3)		Total
Amgen stock	$	417,689,989	$	—	$	—	$	417,689,989
Cash and cash equivalents	5,471,574		—		—		5,471,574
Collective trust funds	—		6,275,138,481		—		6,275,138,481
Common and preferred stocks	92,034,453		—		—		92,034,453
Debt securities	—		2,685		—		2,685
Mutual funds	255,411,543		—		—		255,411,543
Self-directed brokerage accounts	1,117,018,349		2,742,408		—		1,119,760,757

Total investments at fair value	$	1,887,625,908	$	6,277,883,574	$	—	$	8,165,509,482


	Fair value measurements at December 31, 2024, using
	Quoted prices in active markets for identical assets (Level 1)		Significant other observable inputs (Level 2)		Significant unobservable inputs (Level 3)		Total
Amgen stock	$	344,055,715	$	—	$	—	$	344,055,715
Cash and cash equivalents	3,466,558		—		—		3,466,558
Collective trust funds	—		5,003,198,779		—		5,003,198,779
Common and preferred stocks	533,256,711		—		—		533,256,711
Debt securities	—		2,979		—		2,979
Mutual funds	148,845,846		—		—		148,845,846
Self-directed brokerage accounts	996,397,298		3,319,375		—		999,716,673
Total investments at fair value	$	2,026,022,128	$	5,006,521,133	$	—	$	7,032,543,261

Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

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Tabular disclosure of fair value of investment held by employee stock purchase, saving, or similar plan (employee benefit plan (EBP)), including, but not limited to, fair value measured at net asset value per share as practical expedient (NAV).

Employee Benefit Plan, Schedule, Asset Held for Investment (Details) - EBP 001	12 Months Ended
	Dec. 31, 2025 USD ($)
EBP, Schedule of Asset Held for Investment [Line Items]
Entity tax identification number	95-3540776
Plan number	001
Notes Receivable from Participants*	$ 38,602,548
Grand Total	$ 8,950,475,532
Minimum
EBP, Schedule of Asset Held for Investment [Line Items]
Interest Rate	4.25%
Maximum
EBP, Schedule of Asset Held for Investment [Line Items]
Interest Rate	9.50%
Investment, Identifier [Axis]: Capital Preservation Asset Class \| Galliard Intermediate Core Fund L
EBP, Schedule of Asset Held for Investment [Line Items]
Total	$ 461,962,001
Investment, Identifier [Axis]: Capital Preservation Asset Class \| Galliard Short Core Fund F
EBP, Schedule of Asset Held for Investment [Line Items]
Total	284,401,501
Investment, Identifier [Axis]: Capital Preservation Asset Class \| NT Collective Short Term Investment Fund
EBP, Schedule of Asset Held for Investment [Line Items]
Total	53,050,433
Investment, Identifier [Axis]: Capital Preservation Asset Class \| Short-Term Investment Fund II
EBP, Schedule of Asset Held for Investment [Line Items]
Total	39,787,146
Investment, Identifier [Axis]: Capital Preservation Asset Class \| Wrapper Contracts
EBP, Schedule of Asset Held for Investment [Line Items]
Total	0
Investment, Identifier [Axis]: Common Stock \| Amgen stock
EBP, Schedule of Asset Held for Investment [Line Items]
Total	417,689,989
Investment, Identifier [Axis]: Fixed Income Active Asset Class \| BBH Collective Investment Series Trust Series Fund Income Class 1
EBP, Schedule of Asset Held for Investment [Line Items]
Total	181,868,204
Investment, Identifier [Axis]: Fixed Income Active Asset Class \| Banc America Alternative Loan Trust Series 2004-6 Class 4A 15.0% Due 10-25-2048
EBP, Schedule of Asset Held for Investment [Line Items]
Total	$ 1,941
Interest Rate	15.00%
Investment, Identifier [Axis]: Fixed Income Active Asset Class \| FIAM Group Trust For Employees Benefit Plan Core Plus Commingled Pool Class W*
EBP, Schedule of Asset Held for Investment [Line Items]
Total	$ 181,975,209
Investment, Identifier [Axis]: Fixed Income Active Asset Class \| GMAC Mortgage Loan Trust 2003/J10 4.75% Due 01/25/2019
EBP, Schedule of Asset Held for Investment [Line Items]
Total	$ 743
Interest Rate	4.75%
Investment, Identifier [Axis]: Fixed Income Active Asset Class \| Master Asset Security Trust 2004/6 5.25% Due 07/25/2019
EBP, Schedule of Asset Held for Investment [Line Items]
Total	$ 1
Interest Rate	5.25%
Investment, Identifier [Axis]: Fixed Income Active Asset Class \| NT Collective Aggregate Bond Index Fund / Non Lending
EBP, Schedule of Asset Held for Investment [Line Items]
Total	$ 65,981,875
Investment, Identifier [Axis]: Fixed Income Active Asset Class \| NT Collective Short Term Investment Fund
EBP, Schedule of Asset Held for Investment [Line Items]
Total	282
Investment, Identifier [Axis]: Fixed Income Active Asset Class \| Wellington Core Bond Plus Portfolio Collective Investment Trust II
EBP, Schedule of Asset Held for Investment [Line Items]
Total	182,810,908
Investment, Identifier [Axis]: Fixed Income Index Asset Class \| NT Collective Aggregate Bond Index Fund / Non Lending
EBP, Schedule of Asset Held for Investment [Line Items]
Total	970,311,143
Investment, Identifier [Axis]: International Equity Active Asset Class \| Dodge & Cox International Stock Fund
EBP, Schedule of Asset Held for Investment [Line Items]
Total	255,411,543
Investment, Identifier [Axis]: International Equity Active Asset Class \| Great Grey Trust Company GQG Partners International Equity CIT Class C
EBP, Schedule of Asset Held for Investment [Line Items]
Total	248,729,768
Investment, Identifier [Axis]: International Equity Active Asset Class \| Mawer International Equity Collective Investment Trust Class B
EBP, Schedule of Asset Held for Investment [Line Items]
Total	252,538,156
Investment, Identifier [Axis]: International Equity Active Asset Class \| Mondrian Master CIT Focused All Countries World ex-US Equity
EBP, Schedule of Asset Held for Investment [Line Items]
Total	248,622,909
Investment, Identifier [Axis]: International Equity Active Asset Class \| NT Collective MSCI All Country World Index (ACWI) ex/US Index Fund / Non Lending
EBP, Schedule of Asset Held for Investment [Line Items]
Total	50,754,829
Investment, Identifier [Axis]: International Equity Active Asset Class \| Wilmington Trust Collective Investment Trust / Jennison International Equity Opportunities CIT Class J
EBP, Schedule of Asset Held for Investment [Line Items]
Total	248,011,296
Investment, Identifier [Axis]: International Equity Index Asset Class \| NT Collective MSCI All Country World Index (ACWI) ex/US Index Fund / Non Lending
EBP, Schedule of Asset Held for Investment [Line Items]
Total	384,229,509
Investment, Identifier [Axis]: Other \| BIF Money Fund
EBP, Schedule of Asset Held for Investment [Line Items]
Total	1,342,037
Investment, Identifier [Axis]: Other \| Exide Technologies
EBP, Schedule of Asset Held for Investment [Line Items]
Total	24,978
Investment, Identifier [Axis]: Other \| Interest Bearing Cash
EBP, Schedule of Asset Held for Investment [Line Items]
Total	88,742
Investment, Identifier [Axis]: Other \| ML Vanguard Federal Money Market Forfeiture / Settlement
EBP, Schedule of Asset Held for Investment [Line Items]
Total	1,378,351
Investment, Identifier [Axis]: Other \| NT Collective Short Term Investment Fund
EBP, Schedule of Asset Held for Investment [Line Items]
Total	475,614
Investment, Identifier [Axis]: Other \| Tax Reclaims
EBP, Schedule of Asset Held for Investment [Line Items]
Total	2,662,444
Investment, Identifier [Axis]: Participant Self-Directed Accounts
EBP, Schedule of Asset Held for Investment [Line Items]
Total	1,119,760,757
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| AAON Inc.
EBP, Schedule of Asset Held for Investment [Line Items]
Total	236,223
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| Allegion PLC
EBP, Schedule of Asset Held for Investment [Line Items]
Total	1,072,506
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| Ametek Inc.
EBP, Schedule of Asset Held for Investment [Line Items]
Total	3,249,236
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| Amphenol Corporation Class A
EBP, Schedule of Asset Held for Investment [Line Items]
Total	1,882,230
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| Arhaus Inc. Class A
EBP, Schedule of Asset Held for Investment [Line Items]
Total	327,444
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| BWX Technologies Inc.
EBP, Schedule of Asset Held for Investment [Line Items]
Total	2,795,341
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| Balchem Corporation
EBP, Schedule of Asset Held for Investment [Line Items]
Total	525,105
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| Bank Ozk
EBP, Schedule of Asset Held for Investment [Line Items]
Total	667,566
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| Bellring Brands Inc.
EBP, Schedule of Asset Held for Investment [Line Items]
Total	190,130
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| Bio-Techne Corporation
EBP, Schedule of Asset Held for Investment [Line Items]
Total	1,926,851
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| Blackrock Instituitional Trust Company Investment Funds Russell 3000 Alpha Tilts Fund F
EBP, Schedule of Asset Held for Investment [Line Items]
Total	166,892,573
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| Boston Partners CIT Large Capital Value Class E
EBP, Schedule of Asset Held for Investment [Line Items]
Total	157,416,376
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| Brown & Brown Inc.
EBP, Schedule of Asset Held for Investment [Line Items]
Total	1,796,916
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| CCC Intelligent Solutions Holdings Inc.
EBP, Schedule of Asset Held for Investment [Line Items]
Total	478,272
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| CSW Industrials Inc.
EBP, Schedule of Asset Held for Investment [Line Items]
Total	510,742
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| Cabot Corporation
EBP, Schedule of Asset Held for Investment [Line Items]
Total	1,040,662
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| Camtek Limited
EBP, Schedule of Asset Held for Investment [Line Items]
Total	519,283
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| Casella Waste Systems Inc. Class A
EBP, Schedule of Asset Held for Investment [Line Items]
Total	1,092,717
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| Certara Inc.
EBP, Schedule of Asset Held for Investment [Line Items]
Total	344,524
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| Charles River Laboratories International Inc.
EBP, Schedule of Asset Held for Investment [Line Items]
Total	1,950,515
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| Clean Harbors Inc.
EBP, Schedule of Asset Held for Investment [Line Items]
Total	3,650,854
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| Clearwater Analytics Holdings Inc. Class A
EBP, Schedule of Asset Held for Investment [Line Items]
Total	421,015
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| Cohen & Steers Inc.
EBP, Schedule of Asset Held for Investment [Line Items]
Total	222,492
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| Coherent Corporation
EBP, Schedule of Asset Held for Investment [Line Items]
Total	3,403,840
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| Copart Inc.
EBP, Schedule of Asset Held for Investment [Line Items]
Total	833,308
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| Dolby Laboratories Inc.
EBP, Schedule of Asset Held for Investment [Line Items]
Total	1,624,381
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| EnPro Inc.
EBP, Schedule of Asset Held for Investment [Line Items]
Total	647,743
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| Ensign Group Inc.
EBP, Schedule of Asset Held for Investment [Line Items]
Total	809,856
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| Entegris Inc.
EBP, Schedule of Asset Held for Investment [Line Items]
Total	2,955,069
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| Everus Construction Group Inc.
EBP, Schedule of Asset Held for Investment [Line Items]
Total	491,799
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| Fabrinet Company
EBP, Schedule of Asset Held for Investment [Line Items]
Total	720,253
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| Federal Signal Corporation
EBP, Schedule of Asset Held for Investment [Line Items]
Total	727,119
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| First American Financial Corporation
EBP, Schedule of Asset Held for Investment [Line Items]
Total	854,385
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| Five Below Inc.
EBP, Schedule of Asset Held for Investment [Line Items]
Total	447,167
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| Floor & Decor Holdings Inc.
EBP, Schedule of Asset Held for Investment [Line Items]
Total	268,464
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| Freshpet Inc.
EBP, Schedule of Asset Held for Investment [Line Items]
Total	289,600
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| Global-E Online Limited
EBP, Schedule of Asset Held for Investment [Line Items]
Total	468,772
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| Goosehead Insurance Inc. Class A
EBP, Schedule of Asset Held for Investment [Line Items]
Total	256,965
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| Graco Inc.
EBP, Schedule of Asset Held for Investment [Line Items]
Total	998,886
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| Guidewire Software Inc.
EBP, Schedule of Asset Held for Investment [Line Items]
Total	415,890
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| Halozyme Therapeutics Inc.
EBP, Schedule of Asset Held for Investment [Line Items]
Total	1,864,075
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| Hamilton Lane Inc. Class A
EBP, Schedule of Asset Held for Investment [Line Items]
Total	453,565
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| HealthEquity Inc.
EBP, Schedule of Asset Held for Investment [Line Items]
Total	1,156,118
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| Heico Corporation Class A
EBP, Schedule of Asset Held for Investment [Line Items]
Total	1,705,417
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| Henry Schein Inc.
EBP, Schedule of Asset Held for Investment [Line Items]
Total	1,819,211
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| Hexcel Corporation
EBP, Schedule of Asset Held for Investment [Line Items]
Total	1,172,941
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| Huntington Bancshares Inc.
EBP, Schedule of Asset Held for Investment [Line Items]
Total	2,336,420
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| ICF International, Inc.
EBP, Schedule of Asset Held for Investment [Line Items]
Total	473,074
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| IDEX Corporation
EBP, Schedule of Asset Held for Investment [Line Items]
Total	1,524,768
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| Ingredion Inc.
EBP, Schedule of Asset Held for Investment [Line Items]
Total	1,866,481
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| Kadant Inc.
EBP, Schedule of Asset Held for Investment [Line Items]
Total	565,195
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| Keysight Technologies Inc.
EBP, Schedule of Asset Held for Investment [Line Items]
Total	1,893,528
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| LKQ Corporation
EBP, Schedule of Asset Held for Investment [Line Items]
Total	1,359,453
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| Loar Holdings Inc.
EBP, Schedule of Asset Held for Investment [Line Items]
Total	521,968
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| Markel Corporation Holding Company
EBP, Schedule of Asset Held for Investment [Line Items]
Total	451,427
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| Medpace Holdings Inc.
EBP, Schedule of Asset Held for Investment [Line Items]
Total	713,857
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| Mid-American Apartment Communities Inc.
EBP, Schedule of Asset Held for Investment [Line Items]
Total	1,084,609
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| Modine Manufacturing Company
EBP, Schedule of Asset Held for Investment [Line Items]
Total	486,243
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| Moelis & Company Class A
EBP, Schedule of Asset Held for Investment [Line Items]
Total	615,567
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| Morningstar Inc.
EBP, Schedule of Asset Held for Investment [Line Items]
Total	282,720
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| NT Collective Russell 3000 Index Fund / Non Lending
EBP, Schedule of Asset Held for Investment [Line Items]
Total	20,089,652
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| NT Collective Short Term Investment Fund
EBP, Schedule of Asset Held for Investment [Line Items]
Total	2,398,246
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| National Retail Properties Inc.
EBP, Schedule of Asset Held for Investment [Line Items]
Total	724,159
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| Nova Measuring Instruments
EBP, Schedule of Asset Held for Investment [Line Items]
Total	716,875
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| Novanta Inc.
EBP, Schedule of Asset Held for Investment [Line Items]
Total	296,642
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| Nuveen Winslow Large Capital Growth Fund Class C
EBP, Schedule of Asset Held for Investment [Line Items]
Total	220,498,952
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| Ollies Bargain Outlet Holdings Inc.
EBP, Schedule of Asset Held for Investment [Line Items]
Total	527,005
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| Paymentus Holdings Inc. Class A
EBP, Schedule of Asset Held for Investment [Line Items]
Total	593,829
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| Pool Corporation
EBP, Schedule of Asset Held for Investment [Line Items]
Total	64,736
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| Power Integrations Inc.
EBP, Schedule of Asset Held for Investment [Line Items]
Total	1,340,071
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| Procore Technologies Inc.
EBP, Schedule of Asset Held for Investment [Line Items]
Total	880,154
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| Prosperity Bancshares Inc.
EBP, Schedule of Asset Held for Investment [Line Items]
Total	1,220,759
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| Q2 Holdings Inc.
EBP, Schedule of Asset Held for Investment [Line Items]
Total	317,576
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| RBC Bearings Inc.
EBP, Schedule of Asset Held for Investment [Line Items]
Total	900,447
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| RLI Corporation
EBP, Schedule of Asset Held for Investment [Line Items]
Total	332,312
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| Rentokil Initial PLC
EBP, Schedule of Asset Held for Investment [Line Items]
Total	2,075,015
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| SS&C Technologies Holdings Inc.
EBP, Schedule of Asset Held for Investment [Line Items]
Total	3,243,020
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| STERIS plc
EBP, Schedule of Asset Held for Investment [Line Items]
Total	1,507,176
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| Saia Inc.
EBP, Schedule of Asset Held for Investment [Line Items]
Total	490,107
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| Shift4 Payments Inc. Class A
EBP, Schedule of Asset Held for Investment [Line Items]
Total	1,574,375
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| SiteOne Landscape Supply Inc.
EBP, Schedule of Asset Held for Investment [Line Items]
Total	613,333
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| Standex International Corporation
EBP, Schedule of Asset Held for Investment [Line Items]
Total	567,101
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| Trex Company Inc.
EBP, Schedule of Asset Held for Investment [Line Items]
Total	245,735
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| UFP Industries Inc.
EBP, Schedule of Asset Held for Investment [Line Items]
Total	306,839
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| UGI Corporation
EBP, Schedule of Asset Held for Investment [Line Items]
Total	2,240,897
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| Valvoline Inc.
EBP, Schedule of Asset Held for Investment [Line Items]
Total	325,356
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| Vita Coco Company Inc.
EBP, Schedule of Asset Held for Investment [Line Items]
Total	100,878
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| WEX Inc.
EBP, Schedule of Asset Held for Investment [Line Items]
Total	1,205,844
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| Waste Connections Inc.
EBP, Schedule of Asset Held for Investment [Line Items]
Total	3,130,702
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| Wingstop Inc.
EBP, Schedule of Asset Held for Investment [Line Items]
Total	336,986
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| Woodward Inc.
EBP, Schedule of Asset Held for Investment [Line Items]
Total	2,274,353
Investment, Identifier [Axis]: U.S. Equity Active Asset Class \| XPEL Inc.
EBP, Schedule of Asset Held for Investment [Line Items]
Total	396,435
Investment, Identifier [Axis]: U.S. Equity Index Asset Class \| NT Collective Russell 3000 Index Fund / Non Lending
EBP, Schedule of Asset Held for Investment [Line Items]
Total	2,598,695,401
Amgen stock
EBP, Schedule of Asset Held for Investment [Line Items]
Total	417,689,989
Capital Preservation Asset Class:
EBP, Schedule of Asset Held for Investment [Line Items]
Total	839,201,081
Fixed Income Active Asset
EBP, Schedule of Asset Held for Investment [Line Items]
Total	612,639,163
Fixed Income Index Asset
EBP, Schedule of Asset Held for Investment [Line Items]
Total	970,311,143
U.S. Equity Active Asset
EBP, Schedule of Asset Held for Investment [Line Items]
Total	659,305,274
U.S. Equity Index Asset
EBP, Schedule of Asset Held for Investment [Line Items]
Total	2,598,695,401
International Equity Active Asset Class
EBP, Schedule of Asset Held for Investment [Line Items]
Total	1,304,068,501
International Equity Index Asset Class
EBP, Schedule of Asset Held for Investment [Line Items]
Total	384,229,509
Participant Self-Directed Accounts
EBP, Schedule of Asset Held for Investment [Line Items]
Total	1,119,760,757
Other investments
EBP, Schedule of Asset Held for Investment [Line Items]
Total	$ 5,972,166

Summary of Significant Accounting Policies (Policies) - EBP 001	12 Months Ended
	Dec. 31, 2025
EBP, Accounting Standard Update and Change in Accounting Principle [Line Items]
Basis of Accounting	Basis of Accounting The accompanying financial statements are prepared on the accrual basis of accounting. Benefits to participants are recorded when paid.
Fair Value Measurement, Investment Income and Losses, Fully Benefit-Responsive Investment Contracts, and Due from/to Brokers	Fair Value Measurement The investments of the Plan are reported at fair value, except for fully benefit-responsive investment contracts, discussed below. Fair value is generally defined as the price that would be received to sell an asset or paid to transfer a liability (the exit price) in an orderly transaction between market participants at the measurement date (see Note 3, Fair Value Measurements). Investment Income and Losses Dividend income is recognized on the ex-dividend date, and interest income is recorded on an accrual basis. Unrealized gains and losses on investments are measured by the change in the difference between the fair value and cost of the securities held at the beginning of the year (or date purchased if acquired during the Plan year) and the end of the year. Realized gains and losses from security transactions are recorded based on the weighted-average cost of securities sold. Fully Benefit-Responsive Investment Contracts As of December 31, 2025 and 2024, the Plan had fully benefit-responsive investment contracts, including synthetic investment contracts. The synthetic investment contracts are composed of wrapper contracts issued by insurance companies backed by the Plan’s ownership in collective trust funds that invest in fixed income securities. Contract value is the relevant measurement attribute for synthetic investment contracts because this is the amount participants would receive if they were to initiate qualified transactions related to these investments. The issuers of the Plan’s synthetic investment contracts credit the Plan with stated rates of interest, and the issuers guarantee that all qualified participant withdrawals related to the contracts will be at contract value, except as discussed below. The crediting rates provide for realized and unrealized gains and losses on the underlying assets to be amortized over the expected duration of the underlying investments through adjustments to the future interest crediting rates rather than being reflected immediately in the net assets of the Plan. The synthetic investment contracts provide for withdrawals at other than contract value associated with certain events which are not in the ordinary course of Plan operations. These withdrawals are made at contract value, modified by a market value adjustment as defined in the contract. Circumstances which may trigger a market value adjustment are generally defined as any event that, in the reasonable determination of the issuer, has or will have a material adverse effect on the issuer’s interest under the contract. Such events may include, but are not limited to: (a) material amendments to the Plan’s structure or administration; (b) changes in or the creation of competing investment options; (c) complete or partial termination of the Plan; (d) removal of a specifically identifiable group of employees from coverage under the Plan; (e) a change in law, regulation, ruling, administrative position, or accounting standard applicable to the Plan; or (f) communication to Plan participants designed to influence a participant not to invest in the asset class that contains these contracts. The Company does not believe that the occurrence of any such event, which would limit the Plan’s ability to transact at contract value with participants, is probable. These synthetic investment contracts are evergreen contracts with no maturity dates, but do contain termination provisions. The issuer is obligated to pay the excess contract value when the fair value of the underlying investments equals zero. In addition, if the Plan defaults in its obligations under the synthetic investment contract and such default is not corrected within the time permitted by the contract, then the contract may be terminated by the issuer and the Plan will receive the fair value of the underlying investments as of the date of termination. Due from/to Brokers Purchases and sales of investments are recorded on a trade-date basis. Amounts due from and due to brokers arise from unsettled sale and purchase transactions, respectively.
Notes Receivable from Participants	Notes Receivable from Participants Notes receivable from participants are carried at their unpaid balance plus accrued but unpaid interest, as applicable.
Use of Estimates	Use of Estimates The preparation of financial statements in conformity with U.S. generally accepted accounting principles (GAAP) requires management to make estimates and assumptions that affect the amounts reported in the financial statements, accompanying notes and supplemental schedule. Actual results could differ from those estimates.
Risks and Uncertainties	Risks and Uncertainties The Plan provides for investment options representing varied combinations of equities (including Amgen stock), fixed income, and other investments. Investments, in general, particularly in securities, are exposed to various risks, such as interest rate, inflation, market and credit risks, among others. Market risk includes global events which could impact the value of investments, including securities, such as a pandemic or international conflict. Due to the level of risk associated with certain investments, including securities, it is at least reasonably possible that changes in the values of the Plan’s investments, including securities, will occur in the near term and that such changes could materially affect participant account balances and the amounts reported in the Plan’s financial statements.

Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

Disclosure of accounting policy for use of estimate in preparation of financial statement of employee stock purchase, saving, or similar plan (employee benefit plan (EBP)).

Income Tax Status	12 Months Ended
Income Tax Status	Dec. 31, 2025
EBP 001
EBP, Tax Status [Line Items]
Income Tax Status	Income Tax Status The Plan received a determination letter from the IRS dated February 22, 2018, stating that, conditioned on the adoption of proposed Plan amendments submitted to the IRS on February 15, 2018, the Plan is qualified, in form, under Section 401(a) of the Code and, therefore, the related trust is exempt from taxation. There have been eight subsequent amendments to the Plan, including amendments to satisfy the conditions in the determination letter. Once qualified, the Plan is required to operate in conformity with the Code to maintain its qualification. The Company believes the Plan is currently being operated in compliance with the applicable requirements of the Code and, therefore, believes that the Plan is qualified and the related trust is tax exempt. The Company has indicated that it currently intends to continue to take the necessary steps, if any, to maintain the Plan’s compliance with the applicable requirements of the Code.

Fair Value Measurements

12 Months Ended

Dec. 31, 2025

EBP, Investment, Fair Value and NAV [Line Items]

Fair Value Measurements

The Plan uses various valuation approaches in determining the fair value of investments within a hierarchy that maximizes the use of observable inputs and minimizes the use of unobservable inputs by requiring that observable inputs be used when available. Observable inputs are inputs that market participants would use in pricing the investment based on market data obtained from independent sources. Unobservable inputs are inputs that reflect assumptions about the inputs that market participants would use in pricing the investment and are developed based on the best information available in the circumstances.

The fair value hierarchy is divided into three levels based on the source of inputs as follows:

Level 1 – Valuations based on unadjusted quoted prices in active markets for identical investments that the Plan has the ability to access

Level 2 – Valuations for which all significant inputs are observable, either directly or indirectly, other than Level 1 inputs

Level 3 – Valuations based on inputs that are unobservable and significant to the overall fair value measurement

The availability of observable inputs can vary among the various types of investments. To the extent that the valuation is based on models or inputs that are less observable or unobservable in the market, the determination of fair value requires more judgment. In certain cases, the inputs used for measuring fair value may fall into different levels of the fair value hierarchy. In such cases, for financial statement disclosure purposes, the level in the fair value hierarchy within which the fair value measurement is categorized is based on the lowest level of input used that is significant to the overall fair value measurement.

The following fair value hierarchy tables present information about each major class/category of the Plan’s investments measured at fair value:


	Fair value measurements at December 31, 2025, using
	Quoted prices in active markets for identical assets (Level 1)		Significant other observable inputs (Level 2)		Significant unobservable inputs (Level 3)		Total
Amgen stock	$	417,689,989	$	—	$	—	$	417,689,989
Cash and cash equivalents	5,471,574		—		—		5,471,574
Collective trust funds	—		6,275,138,481		—		6,275,138,481
Common and preferred stocks	92,034,453		—		—		92,034,453
Debt securities	—		2,685		—		2,685
Mutual funds	255,411,543		—		—		255,411,543
Self-directed brokerage accounts	1,117,018,349		2,742,408		—		1,119,760,757

Total investments at fair value	$	1,887,625,908	$	6,277,883,574	$	—	$	8,165,509,482


	Fair value measurements at December 31, 2024, using
	Quoted prices in active markets for identical assets (Level 1)		Significant other observable inputs (Level 2)		Significant unobservable inputs (Level 3)		Total
Amgen stock	$	344,055,715	$	—	$	—	$	344,055,715
Cash and cash equivalents	3,466,558		—		—		3,466,558
Collective trust funds	—		5,003,198,779		—		5,003,198,779
Common and preferred stocks	533,256,711		—		—		533,256,711
Debt securities	—		2,979		—		2,979
Mutual funds	148,845,846		—		—		148,845,846
Self-directed brokerage accounts	996,397,298		3,319,375		—		999,716,673
Total investments at fair value	$	2,026,022,128	$	5,006,521,133	$	—	$	7,032,543,261

The fair values of substantially all common stocks (including Amgen stock), preferred stocks, publicly traded mutual funds and underlying investments of self-directed brokerage accounts are valued using quoted market prices in active markets with no valuation adjustment.

Collective trust funds represent interests in pooled investment vehicles designed typically for collective investment of employee benefit trusts. The fair values of these investments are determined by reference to the net asset value per unit provided by the fund managers as the basis for current transactions.

Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

The entire disclosure for fair value of investment held by employee stock purchase, saving, or similar plan (employee benefit plan (EBP)), including, but not limited to, fair value measured at net asset value per share as practical expedient (NAV).

Reference 1: http://www.xbrl.org/2003/role/disclosureRef
-Topic 820
-SubTopic 10
-Name Accounting Standards Codification
-Section 50
-Paragraph 3
-Subparagraph (b)
-Publisher FASB
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Reference 2: http://www.xbrl.org/2003/role/disclosureRef
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-SubTopic 10
-Name Accounting Standards Codification
-Section 50
-Paragraph 3
-Subparagraph (a)
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Reference 3: http://www.xbrl.org/2003/role/exampleRef
-Topic 962
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-Paragraph 17
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147478873/962-325-55-17

Reference 4: http://www.xbrl.org/2003/role/disclosureRef
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-SubTopic 10
-Name Accounting Standards Codification
-Section 50
-Paragraph 6A
-Subparagraph (a)
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Reference 5: http://www.xbrl.org/2003/role/disclosureRef
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-Paragraph 6A
-Subparagraph (d)
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Reference 6: http://www.xbrl.org/2003/role/disclosureRef
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Reference 7: http://www.xbrl.org/2003/role/disclosureRef
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Reference 8: http://www.xbrl.org/2003/role/disclosureRef
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Reference 9: http://www.xbrl.org/2003/role/disclosureRef
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Reference 10: http://www.xbrl.org/2003/role/disclosureRef
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Reference 11: http://www.xbrl.org/2003/role/disclosureRef
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Reference 12: http://www.xbrl.org/2003/role/disclosureRef
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Reference 13: http://www.xbrl.org/2003/role/disclosureRef
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Reference 14: http://www.xbrl.org/2003/role/disclosureRef
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Reference 15: http://www.xbrl.org/2003/role/disclosureRef
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Reference 16: http://www.xbrl.org/2003/role/recommendedDisclosureRef
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Reference 17: http://www.xbrl.org/2003/role/disclosureRef
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-URI https://asc.fasb.org/1943274/2147477509/962-325-45-6

Statement of Changes in Net Assets Available for Benefits - EBP 001	12 Months Ended
	Dec. 31, 2025 USD ($)
Additions to (deductions from) net assets:
Employer contributions	$ 287,949,077
Participant contributions	254,053,776
Rollover contributions	45,442,845
Interest and dividend income	58,852,063
Net realized/unrealized gains	1,207,787,460
Interest income on notes receivable from participants	2,830,276
Benefits paid	(640,689,220)
Investment and administrative fees	(8,193,031)
Net increase	1,208,033,246
Net assets available for benefits at beginning of year	7,755,448,034
Net assets available for benefits at end of year	$ 8,963,481,280

Income Tax Status (Details)	Dec. 31, 2025 class
EBP 001
EBP, Tax Status [Line Items]
Number of amendments	8

Summary of Significant Accounting Policies

12 Months Ended

Dec. 31, 2025

EBP, Accounting Standard Update and Change in Accounting Principle [Line Items]

Summary of Significant Accounting Policies

Basis of Accounting

The accompanying financial statements are prepared on the accrual basis of accounting. Benefits to participants are recorded when paid.

Fair Value Measurement

The investments of the Plan are reported at fair value, except for fully benefit-responsive investment contracts, discussed below. Fair value is generally defined as the price that would be received to sell an asset or paid to transfer a liability (the exit price) in an orderly transaction between market participants at the measurement date (see Note 3, Fair Value Measurements).

Investment Income and Losses

Dividend income is recognized on the ex-dividend date, and interest income is recorded on an accrual basis. Unrealized gains and losses on investments are measured by the change in the difference between the fair value and cost of the securities held at the beginning of the year (or date purchased if acquired during the Plan year) and the end of the year. Realized gains and losses from security transactions are recorded based on the weighted-average cost of securities sold.

Fully Benefit-Responsive Investment Contracts

As of December 31, 2025 and 2024, the Plan had fully benefit-responsive investment contracts, including synthetic investment contracts. The synthetic investment contracts are composed of wrapper contracts issued by insurance companies backed by the Plan’s ownership in collective trust funds that invest in fixed income securities. Contract value is the relevant measurement attribute for synthetic investment contracts because this is the amount participants would receive if they were to initiate qualified transactions related to these investments. The issuers of the Plan’s synthetic investment contracts credit the Plan with stated rates of interest, and the issuers guarantee that all qualified participant withdrawals related to the contracts will be at contract value, except as discussed below. The crediting rates provide for realized and unrealized gains and losses on the underlying assets to be amortized over the expected duration of the underlying investments through adjustments to the future interest crediting rates rather than being reflected immediately in the net assets of the Plan.

The contract values of the Plan’s synthetic investment contracts were as follows:


	December 31,
	2025		2024
Synthetic investment contracts	$	761,085,480	$	688,059,315

Total fully benefit-responsive investment contracts	$	761,085,480	$	688,059,315

The synthetic investment contracts provide for withdrawals at other than contract value associated with certain events which are not in the ordinary course of Plan operations. These withdrawals are made at contract value, modified by a market value adjustment as defined in the contract. Circumstances which may trigger a market value adjustment are generally defined as any event that, in the reasonable determination of the issuer, has or will have a material adverse effect on the issuer’s interest under the contract. Such events may include, but are not limited to: (a) material amendments to the Plan’s structure or administration; (b) changes in or the creation of competing investment options; (c) complete or partial termination of the Plan; (d) removal of a specifically identifiable group of employees from coverage under the Plan; (e) a change in law, regulation, ruling, administrative position, or accounting standard applicable to the Plan; or (f) communication to Plan participants designed to influence a participant not to invest in the asset class that contains these contracts. The Company does not believe that the occurrence of any such event, which would limit the Plan’s ability to transact at contract value with participants, is probable.

These synthetic investment contracts are evergreen contracts with no maturity dates, but do contain termination provisions. The issuer is obligated to pay the excess contract value when the fair value of the underlying investments equals zero. In addition, if the Plan defaults in its obligations under the synthetic investment contract and such default is not corrected within the time permitted by the contract, then the contract may be terminated by the issuer and the Plan will receive the fair value of the underlying investments as of the date of termination.

Notes Receivable from Participants

Notes receivable from participants are carried at their unpaid balance plus accrued but unpaid interest, as applicable.

Due from/to Brokers

Purchases and sales of investments are recorded on a trade-date basis. Amounts due from and due to brokers arise from unsettled sale and purchase transactions, respectively.

Use of Estimates

The preparation of financial statements in conformity with U.S. generally accepted accounting principles (GAAP) requires management to make estimates and assumptions that affect the amounts reported in the financial statements, accompanying notes and supplemental schedule. Actual results could differ from those estimates.

Risks and Uncertainties

The Plan provides for investment options representing varied combinations of equities (including Amgen stock), fixed income, and other investments. Investments, in general, particularly in securities, are exposed to various risks, such as interest rate, inflation, market and credit risks, among others. Market risk includes global events which could impact the value of investments, including securities, such as a pandemic or international conflict. Due to the level of risk associated with certain investments, including securities, it is at least reasonably possible that changes in the values of the Plan’s investments, including securities, will occur in the near term and that such changes could materially affect participant account balances and the amounts reported in the Plan’s financial statements.

Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.