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If the entity operates in more than one business, the disclosure also indicates the relative importance of its operations in each business and the basis for the determination (for example, assets, revenues, or earnings). Disclosures about the nature of operations need not be quantified; relative importance could be conveyed by use of terms such as "predominately", "about equally", or "major and other". This element is also referred to as "Business Description". 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Use of estimates Use of Estimates, Policy [Policy Text Block] Cash and cash equivalents Cash and Cash Equivalents, Fair Value Disclosure Acquisitions and divestitures Business Combination Disclosure [Text Block] Other comprehensive income, net of reclassification adjustments and taxes: Other Comprehensive Income (Loss), Net of Tax, Portion Attributable to Parent [Abstract] Accounts payable Increase (Decrease) in Accounts Payable Fair value adjustments Cumulative amounts of fair value hedging adjustments related to the carrying amounts of the hedged liabilities Hedged Liability, Fair Value Hedge, Cumulative Increase (Decrease) Subsequent Events [Abstract] Investments Investments in Debt and Marketable Equity Securities (and Certain Trading Assets) Disclosure [Text Block] Income taxes Income Tax Disclosure [Text Block] Extinguishment of debt Payment for Debt Extinguishment or Debt Prepayment Cost Finished goods Inventory, Finished Goods, Net of Reserves Amortization charges associated with finite-lived intangible assets Amortization of Intangible Assets Schedule of goodwill Schedule of Goodwill [Table Text Block] Basic (in usd per share) Basic EPS (in usd per share) Earnings Per Share, Basic Total unrealized gains (losses) Other Comprehensive Income (Loss), Cash Flow Hedge, Gain (Loss), after Reclassification, before Tax Five Prime Therapeutics, Inc. 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Unrealized gain (loss) recognized in Other Comprehensive Income for our derivative instruments designated as cash flow hedges Schedule of Cash Flow Hedges Included in Accumulated Other Comprehensive Income (Loss) [Table Text Block] Fair value of each major class of financial assets and liabilities measured at fair value on a recurring basis Schedule of Fair Value, Assets and Liabilities Measured on Recurring Basis [Table Text Block] Long-term tax liabilities Liability for Uncertainty in Income Taxes, Noncurrent 4.663% notes due 2051 (4.663% 2051 Notes) [Member] Four Point Six Six Three Percent Notes Due Two Zero Five One [Member] Four Point Six Six Three Percent Notes Due Two Zero Five One [Member] Deferred tax asset Business Combination Recognized Identifiable Assets Acquired and Liabilities Assumed, Deferred Tax Assets Other products Other Products [Member] Other Products [Member] Percentage of prinicipal amount of notes that may be paid upon occurance of change in control triggering event Percentage of Prinicipal Amount of Notes that may be Paid Upon Occurance of Change in Control Triggering Event Percentage of Prinicipal Amount of Notes that may be Paid Upon Occurance of Change in Control Triggering Event Cash and cash equivalents at beginning of period Cash and cash equivalents at end of period Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents Prolia Prolia [Member] Prolia. 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and development Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Indefinite-Lived Intangible Assets Summary of significant accounting policies Significant Accounting Policies [Text Block] 4.563% notes due 2048 (4.563% 2048 Notes) [Member] 4.563% notes due 2048 (4.563% 2048 Notes) [Member] Four Point Five Six Three Percent Notes Due Two Zero Four Eight [Member] Four Point Five Six Three Percent Notes Due Two Zero Four Eight [Member] Other Other Long-Term Debt Repurchases of common stock (in shares) Stock Repurchased and Retired During Period, Shares Trade receivables, net Increase (Decrease) in Accounts Receivable Title of 12(b) Security Title of 12(b) Security Long-term debt, fair value Notes Payable, Fair Value Disclosure Total operating expenses Costs and Expenses Other revenues Product and Service, Other [Member] Subsequent Event [Line Items] Subsequent Event [Line Items] 2.45% notes due 2030 (2.45% 2030 Notes) [Member] Two Point Four Five 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Assets 3.00% 2029 Notes [Member] 3.00% 2029 Notes [Member] 3.00% 2029 Notes Hedging Relationship [Domain] Hedging Relationship [Domain] Hedging Designation [Axis] Hedging Designation [Axis] R & D Technology rights R & D Technology rights [Member] R & D Technology rights [Member] Entity Filer Category Entity Filer Category 3.625% notes due 2024 (3.625% 2024 Notes) [Member] Three Point Six Two Five Percent Notes Due 2024 [Member] Three Point Six Two Five Percent Notes Due 2024 [Member] Basic (in shares) Weighted-average shares for basic EPS (in shares) Weighted Average Number of Shares Outstanding, Basic U.S. UNITED STATES Liabilities: Liabilities, Fair Value Disclosure [Abstract] Alternative investments Alternative Investment Ownership percentage Equity Method Investment, Ownership Percentage Contingencies and commitments Commitments and Contingencies Security Exchange Name Security Exchange Name Weighted average period of amortization Acquired Finite-Lived Intangible Assets, Weighted Average Useful Life Notional amounts Derivative, Notional Amount Held-for-sale assets Disposal Group, Including Discontinued Operation, Assets, Current Total revenues Revenue from Contract with Customer, Excluding Assessed Tax Accrued income taxes, net Increase (Decrease) in Income Taxes Payable 1.65% notes due 2028 (1.65% 2028 Notes) [Member} One point six five percent 2028 Notes [Member] One point six five percent 2028 Notes Cover [Abstract] Cover [Abstract] Schedule of Long-term Debt Instruments [Table] Schedule of Long-Term Debt Instruments [Table] Significant unobservable inputs (Level 3) Fair Value, Inputs, Level 3 [Member] Income before income taxes Income before income taxes Income (Loss) from Continuing Operations before Equity Method Investments, Income Taxes, Noncontrolling Interest Proposed additional income tax Proposed additional income tax Proposed additional income tax 2.60% notes due 2026 (2.60% 2026 notes) [Member] Two Point Six Zero Notes Due Two Zero Two Six [Member] Two Point Six Zero Notes Due Two Zero Two Six [Member] Work in process Inventory, Work in Process, Net of Reserves Business Combinations [Abstract] Business Combinations [Abstract] Derivatives: Derivative Assets Fair Value Disclosure [Abstract] Derivative assets. Number of Third-Party Financial Institutions Number of Third-Party Financial Institutions Number of Third-Party Financial Institutions Revenues Revenue from Contract with Customer [Text Block] Other Accumulated Other Adjustment Attributable to Parent [Member] Accumulated Other Adjustment Attributable to Parent [Member] Revenue from External Customers by Products and Services [Table] Revenue from External Customers by Products and Services [Table] Investments [Domain] Investments [Domain] Forecast Forecast [Member] Otezla Otezla [Member] Otezla [Member] Total liabilities and stockholders’ equity Liabilities and Equity Gains (losses) on fair value hedging relationships, Hedged items Change in Unrealized Gain (Loss) on Hedged Item in Fair Value Hedge Reclassification out of Accumulated Other Comprehensive Income [Line Items] Reclassification Adjustment out of Accumulated Other Comprehensive Income [Line Items] Long-term Debt, Type [Axis] Long-Term Debt, Type [Axis] Goodwill [Roll Forward] Goodwill [Roll Forward] Extinguishment of debt Extinguishment of Debt, Amount Amount available for stock repurchases under a board approved stock repurchase plan Stock Repurchase Program, Remaining Authorized Repurchase Amount Cash Cash Derivatives: Derivative Financial Instruments Liabilities Fair Value Disclosure [Abstract] Derivative financial instruments liabilities fair value disclosure. ROW Non-US [Member] Derivatives not designated as hedging instrument Not Designated as Hedging Instrument [Member] Disposal Group Name [Domain] Disposal Group Name [Domain] Cash paid for acquisitions, net of cash acquired Payments to acquire business Payments to Acquire Businesses, Net of Cash Acquired Significant other observable inputs (Level 2) Fair Value, Inputs, Level 2 [Member] Current Fiscal Year End Date Current Fiscal Year End Date 2.00% €750 million notes due 2026 (2.00% 2026 euro Notes) 2.00% 2026 euro Notes Two Percent Euro Notes Due Two Thousand Twenty Six [Member] Two Percent Euro Notes Due Two Thousand Twenty Six [Member] Finite-Lived Intangible Assets [Line Items] Finite-Lived Intangible Assets [Line Items] Including discontinued operation, assets Disposal Group, Including Discontinued Operation, Assets Intangible assets, net Intangible assets, net Intangible Assets, Net (Excluding Goodwill) Diluted (in usd per share) Diluted EPS (in usd per share) Earnings Per Share, Diluted ChemoCentryx, Inc. ChemoCentryx, Inc. [Member] ChemoCentryx, Inc. Stock-based compensation expense APIC, Share-Based Payment Arrangement, Increase for Cost Recognition Total current liabilities Liabilities, Current Other current assets Other Assets, Current Schedule of Available-for-sale Securities [Table] Schedule of Available-for-Sale Securities [Table] Research and development technology rights Acquired Research And Development Technology Rights [Member] Acquired research and development technology rights. Share Repurchase Program [Axis] Share Repurchase Program [Axis] Fair Values Derivatives Balance Sheet Location By Derivative Contract Type By Hedging Designation [Table] Fair Values Derivatives, Balance Sheet Location, by Derivative Contract Type [Table] Equity Securities, FV-NI, Unrealized Gain (Loss) Equity Securities, FV-NI, Unrealized Gain (Loss) AMG 340 AMG 340 [Member] AMG 340 Total derivative assets, fair value Derivative Asset, Subject to Master Netting Arrangement, before Offset Entity Address, Address Line One Entity Address, Address Line One Income Tax Authority [Domain] Income Tax Authority [Domain] Other Proceeds from (Payments for) Other Financing Activities Product and Service [Axis] Product and Service [Axis] Class of Stock [Domain] Class of Stock [Domain] Neumora Therapeutics, Inc. Neumora Therapeutics, Inc. [Member] Neumora Therapeutics, Inc. Fair Value Disclosures [Abstract] Fair Value Disclosures [Abstract] Derivative Instruments and Hedging Activities Disclosure [Abstract] Derivative Instruments and Hedging Activities Disclosure [Abstract] Interest rate swap contracts Interest Rate Fair Value Hedge Asset at Fair Value Exchange [Domain] Exchange [Domain] Teneobio Inc. Teneobio Inc. [Member] Teneobio Inc. ChemoCentryx, Inc. Securities Matters ChemoCentryx, Inc. Securities Matters [Member] ChemoCentryx, Inc. Securities Matters Inventories Inventory Disclosure [Text Block] United States of America, Dollars United States of America, Dollars Schedule of borrowings Schedule of Long-Term Debt Instruments [Table Text Block] Equity [Abstract] Equity [Abstract] Subsequent Event [Table] Subsequent Event [Table] Inventory Disclosure [Abstract] Inventory Disclosure [Abstract] Entity Tax Identification Number Entity Tax Identification Number Derivatives Fair Value [Line Items] Derivatives, Fair Value [Line Items] Foreign currency and cross-currency swap contracts Foreign Currency Contract, Asset, Fair Value Disclosure Interest rates Derivative, Fixed Interest Rate Number of class action suits Loss Contingency, Number Of Class Action Suits Loss Contingency, Number Of Class Action Suits Hedged Liability, Fair Value Hedge Hedged Liability, Fair Value Hedge Disaggregation of revenue by product and by geographic area Disaggregation of Revenue [Table Text Block] Other short-term interest-bearing securities Other Short Term Interest Bearing Securities [Member] Other short-term interest bearing securities. Revenue from Contract with Customer [Abstract] Revenue from Contract with Customer [Abstract] Total estimated amortization of finite-lived intangible assets for the remainder of the year Finite-Lived Intangible Asset, Expected Amortization, Remainder of Fiscal Year 3.15% notes due 2040 (3.15% 2040 Notes) [Member] Three Point One Five Percent Notes Due 2040 [Member] Three Point One Five Percent Notes Due 2040 [Member] Research and development Research and Development Expense (Excluding Acquired in Process Cost) Nplate Nplate [Member] Nplate Increase in cash and cash equivalents Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Period Increase (Decrease), Including Exchange Rate Effect Payments Business Combination, Contingent Consideration Arrangements, Payments Business Combination, Contingent Consideration Arrangements, Payments Proposed additional income tax 2013-2015 Proposed additional income tax 2013-2015 Proposed additional income tax 2013-2015 Effect of dilutive securities (in shares) Weighted Average Number of Shares Outstanding, Diluted, Adjustment Total estimated amortization of finite-lived intangible assets for year five Finite-Lived Intangible Asset, Expected Amortization, Year Five Entity Central Index Key Entity Central Index Key Finite-Lived Intangible Assets by Major Class [Axis] Finite-Lived Intangible Assets by Major Class [Axis] Tax impact related to employee stock-based compensation expense Share-Based Payment Arrangement, Decrease for Tax Withholding Obligation Total consideration Business Combination, Consideration Transferred Accrued liabilities/ Other noncurrent liabilities Accrued Liabilities Other Non Current Liabilities [Member] Accrued liabilities/other non-current liabilities. City Area Code City Area Code ASSETS Assets [Abstract] Long-term Debt, Type [Domain] Long-Term Debt, Type [Domain] Euro Member Countries, Euro Euro Member Countries, Euro Statement of Stockholders' Equity [Abstract] Statement of Stockholders' Equity [Abstract] Notes Notes Payable to Banks [Member] Proceeds from maturities of marketable securities Proceeds from Maturities, Prepayments and Calls of Debt Securities, Available-for-Sale Cash flows from financing activities: Net Cash Provided by (Used in) Financing Activities [Abstract] Payments to Acquire Equity Method Investments Payments to Acquire Equity Method Investments Computation of basic and diluted earnings per share Basic And Diluted Earning Per Share [Abstract] Basic and diluted earning per share. Other noncurrent liabilities Other Liabilities, Noncurrent Income (Loss) from Equity Method Investments Income (Loss) from Equity Method Investments Disposal Group Classification [Domain] Disposal Group Classification [Domain] Other liabilities Increase (Decrease) in Other Operating Liabilities Purchases of property, plant and equipment Payments to Acquire Property, Plant, and Equipment Total estimated amortization of finite-lived intangible assets for year one Finite-Lived Intangible Asset, Expected Amortization, Year One Computation for basic and diluted earnings per share Schedule of Earnings Per Share, Basic and Diluted [Table Text Block] Equity Method Investment, Aggregate Cost Equity Method Investment, Aggregate Cost