0000001 - Document - Cover Page link:presentationLink link:calculationLink link:definitionLink 9952151 - Statement - CONDENSED CONSOLIDATED STATEMENTS OF INCOME link:presentationLink link:calculationLink link:definitionLink 9952152 - Statement - CONDENSED CONSOLIDATED STATEMENTS OF COMPREHENSIVE INCOME link:presentationLink link:calculationLink link:definitionLink 9952153 - Statement - CONDENSED CONSOLIDATED BALANCE SHEETS link:presentationLink link:calculationLink link:definitionLink 9952154 - Statement - CONDENSED CONSOLIDATED BALANCE SHEETS (Parenthetical) link:presentationLink link:calculationLink link:definitionLink 9952155 - Statement - CONDENSED CONSOLIDATED STATEMENTS OF STOCKHOLDERS’ EQUITY link:presentationLink link:calculationLink link:definitionLink 9952156 - Statement - CONDENSED CONSOLIDATED STATEMENTS OF STOCKHOLDERS’ EQUITY (Parenthetical) link:presentationLink link:calculationLink link:definitionLink 9952157 - Statement - CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS link:presentationLink link:calculationLink link:definitionLink 9952158 - Disclosure - Summary of significant accounting policies link:presentationLink link:calculationLink link:definitionLink 9952159 - Disclosure - Acquisitions link:presentationLink link:calculationLink link:definitionLink 9952160 - Disclosure - Revenues link:presentationLink link:calculationLink link:definitionLink 9952161 - Disclosure - Income taxes link:presentationLink link:calculationLink link:definitionLink 9952162 - Disclosure - Earnings per share link:presentationLink link:calculationLink link:definitionLink 9952163 - Disclosure - Investments link:presentationLink link:calculationLink link:definitionLink 9952164 - Disclosure - Inventories link:presentationLink link:calculationLink link:definitionLink 9952165 - Disclosure - Goodwill and other intangible assets link:presentationLink link:calculationLink link:definitionLink 9952166 - Disclosure - Financing arrangements link:presentationLink link:calculationLink link:definitionLink 9952167 - Disclosure - Stockholders' equity link:presentationLink link:calculationLink link:definitionLink 9952168 - Disclosure - Fair value measurement link:presentationLink link:calculationLink link:definitionLink 9952169 - Disclosure - Derivative instruments link:presentationLink link:calculationLink link:definitionLink 9952170 - Disclosure - Contingencies and commitments link:presentationLink link:calculationLink link:definitionLink 9954471 - Disclosure - Summary of significant accounting policies (Policies) link:presentationLink link:calculationLink link:definitionLink 9954472 - Disclosure - Acquisitions (Tables) link:presentationLink link:calculationLink link:definitionLink 9954473 - Disclosure - Revenues (Tables) link:presentationLink link:calculationLink link:definitionLink 9954474 - Disclosure - Earnings per share (Tables) link:presentationLink link:calculationLink link:definitionLink 9954475 - Disclosure - Investments (Tables) link:presentationLink link:calculationLink link:definitionLink 9954476 - Disclosure - Inventories (Tables) link:presentationLink link:calculationLink link:definitionLink 9954477 - Disclosure - Goodwill and other intangible assets (Tables) link:presentationLink link:calculationLink link:definitionLink 9954478 - Disclosure - Financing arrangements (Tables) link:presentationLink link:calculationLink link:definitionLink 9954479 - Disclosure - Stockholders' equity (Tables) link:presentationLink link:calculationLink link:definitionLink 9954480 - Disclosure - Fair value measurement (Tables) link:presentationLink link:calculationLink link:definitionLink 9954481 - Disclosure - Derivative instruments (Tables) link:presentationLink link:calculationLink link:definitionLink 9954482 - Disclosure - Summary of significant accounting policies (Details) link:presentationLink link:calculationLink link:definitionLink 9954483 - Disclosure - Acquisitions - Acquisition of Horizon Therapeutics plc (Details) link:presentationLink link:calculationLink link:definitionLink 9954484 - Disclosure - Acquisitions - Schedule of Business Acquisitions, by Acquisition (Details) link:presentationLink link:calculationLink link:definitionLink 9954485 - Disclosure - Acquisitions - Supplemental Pro Forma Financial Information (Details) link:presentationLink link:calculationLink link:definitionLink 9954486 - Disclosure - Revenues - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9954487 - Disclosure - Revenues - Disaggregation of Revenue by Product and by Geographic Area (Details) link:presentationLink link:calculationLink link:definitionLink 9954488 - Disclosure - Income taxes (Details) link:presentationLink link:calculationLink link:definitionLink 9954489 - Disclosure - Earnings per share - Computation for Basic and Diluted EPS (Details) link:presentationLink link:calculationLink link:definitionLink 9954490 - Disclosure - Investments - Schedule of Available-For-Sale Investments (Details) link:presentationLink link:calculationLink link:definitionLink 9954491 - Disclosure - Investments - Schedule of Fair Values by Classification (Details) link:presentationLink link:calculationLink link:definitionLink 9954492 - Disclosure - Investments - Available-For-Sale (Details) link:presentationLink link:calculationLink link:definitionLink 9954493 - Disclosure - Investments - BeiGene, Ltd. (Details) link:presentationLink link:calculationLink link:definitionLink 9954494 - Disclosure - Investments - Other Equity Securities (Details) link:presentationLink link:calculationLink link:definitionLink 9954495 - Disclosure - Investments - Neumora Therapeutics, Inc. (Details) link:presentationLink link:calculationLink link:definitionLink 9954496 - Disclosure - Investments - Limited Partnership (Details) link:presentationLink link:calculationLink link:definitionLink 9954497 - Disclosure - Inventories (Details) link:presentationLink link:calculationLink link:definitionLink 9954498 - Disclosure - Goodwill and other intangible assets - Schedule of Goodwill (Details) link:presentationLink link:calculationLink link:definitionLink 9954499 - Disclosure - Goodwill and other intangible assets - Schedule of Identifiable Intangible Assets (Details) link:presentationLink link:calculationLink link:definitionLink 9954500 - Disclosure - Goodwill and other intangible assets - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9954501 - Disclosure - Financing arrangements - Schedule of Borrowings (Details) link:presentationLink link:calculationLink link:definitionLink 9954502 - Disclosure - Financing arrangements - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9954503 - Disclosure - Stockholders' equity - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9954504 - Disclosure - Stockholders' equity - Components of Accumulated Other Comprehensive Income (Details) link:presentationLink link:calculationLink link:definitionLink 9954505 - Disclosure - Stockholders' equity - Reclassifications Out of Accumulated Other Comprehensive Income (Details) link:presentationLink link:calculationLink link:definitionLink 9954506 - Disclosure - Fair value measurement - Fair Value of Financial Assets and Liabilities on Recurring Basis (Details) link:presentationLink link:calculationLink link:definitionLink 9954507 - Disclosure - Fair value measurement - Contingent Consideration Obligations (Details) link:presentationLink link:calculationLink link:definitionLink 9954508 - Disclosure - Fair value measurement - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9954509 - Disclosure - Derivative instruments - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9954510 - Disclosure - Derivative instruments - Schedule of Cross-Currency Swaps (Details) link:presentationLink link:calculationLink link:definitionLink 9954511 - Disclosure - Derivative instruments - Summary of Unrealized Gains and Losses Recognized in AOCI (Details) link:presentationLink link:calculationLink link:definitionLink 9954512 - Disclosure - Derivative instruments - Hedged Liabilities and Cumulative Amount (Details) link:presentationLink link:calculationLink link:definitionLink 9954513 - Disclosure - Derivative instruments - Summary of Income and Expense Line Items (Details) link:presentationLink link:calculationLink link:definitionLink 9954514 - Disclosure - Derivative instruments - Fair Value of Derivatives (Details) link:presentationLink link:calculationLink link:definitionLink 9954515 - Disclosure - Contingencies and commitments - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink